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In present study various pharmacological investigation of alkaline water compiled, now days due to fast life acidity become a huge problem in metro cities which is origin for various diseases such a GERD, hypertension, skin diseases, hyperthyroidism, hyperlipidemia, cancer, diabetes etc. Various researches worked on activity of alkaline water and various clinical trials are in tunnel. Compile date elucidate the importance of alkaline water in various diseases treatments and future prospectus in clinical trials of various cancer and related diseases.

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