Linked article: This article is commentary on by F. Forton et al., pp. e47–e48 in this issue. To view this article visit https://doi.org/10.1111/jdv.15162
The aim of the study was to identify Bacillus species from the
Demodex folliculorum of patients with topical
steroidinduced facial rosaceiform dermatitis. Of the 75 patients examined, 20%
had clinical spinulosis, while 18.66% had dermoscopic features of
Demodex: follicular plugs and tails. Of the 17.33% positive
patients identified upon microscopy for Demodex, samples for
bacterial culture were plated on trypticase soy Colombia agar. Identification
was performed by microorganisms grown method mass spectrometry. We identified a
strain of Bacillus cereus.
The interrelations and sequencing of interleukins are complex (inter)actions where each interleukin can stimulate the secretion of its preceding interleukin. In this paper, we attempt to summarize the currently known roles of IL-4, IL-13, IL-31, and IL-33 from a multi-disciplinary perspective. In order to conduct a comprehensive review of the current literature, a search was conducted using PubMed, Google Scholar, Medscape, UpToDate, and Key Elsevier for keywords. The results were compiled from case reports, case series, letters, and literature review papers, and analyzed by a panel of multi-disciplinary specialist physicians for relevance. Based on 173 results, we compiled the following review of interleukin signaling and its clinical significance across a multitude of medical specialties. Interleukins are at the bed rock of a multitude of pathologies across different organ systems and understanding their role will likely lead to novel treatments and better outcomes for our patients. New interleukins are being described, and the role of this inflammatory cascade is still coming to light. We hope this multi-discipline review on the role interleukins play in current pathology assists in this scope.
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