The synthesis of a series of 2,2-disubstituted-5-cyanocyclopentanones by hydrolysis of the precursor 3,3-disubstituted-2-amino-1-cyanocyclopente~es (2,2-disubstituted-5-cyanocyclopentanoneirnines) is described. The new compounds possess the following substituents: dimethyl, diethyl, phenyl hydrogen, and ethyl phenyl.
The preparation of several potential analgetics derived from -,2-diphenylcyclopentanone and the reaction of some intermediate compounds is reported. An improved synthesis of the ketone is demonstrated.' 2) IF N. Craig and I. .
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