Hydrazones, Semicarbazones, and Other Nitrogenous Substances Reqiring Reductive Pretreatment

Semimicro-Kjeldahl Procedure for Pyridinium Halide and Oxyhalide Salts

“…Allow the digestion mixture to cool and then proceed with the conventional distillation and titration (6). Apparently tin, or some oxidation state of tin, had a beneficial effect.…”

“…Nitrogen present in a chain, as in amides and amines, is considered easier to determine than that present in ring structures, nitrogen-nitrogen linkages, and nitrogenoxygen linkages. However, with various modifications of the digestion procedures or a predigestion treatment of the organic nitrogen, this method of analysis is applicable to a wide variety of compounds (1)(2)(3)(4)(5)(6)(7).…”

Organic Microchemistry

“…Fish (50), Konovalov (105), Pepkowitz (142), and Ogg and Willits (137) all reported on the analyses of materials containing N-N and N-O linkages. Fish used reduction with zinc and hydrochloric acid in acetic acid or methanol, while Konovalov heated the materials in sealed tubes with hydriodic acid.…”

Volumetric Analytical Methods for Organic Compounds

“…The Kjeldahl method is adapted to the analysis of azines, hydrazones, oximes, semicarbazones, other compounds containing N-O linkages, and derivatives of pyridine and quinoline. The material is dissolved in glacial acetic acid and methanol, reduced with zinc and hydrochloric acid, and digested, and the nitrogen is determined by Cole and Park's procedure (47).…”