This paper aims to answer the question, if a generic approach for Model-Driven Design of e-Applications exists. A proposal for generic approach on Model-Driven Design applied in different application scenarios for e-Government, e-Business and eLearning is introduced. Identified solutions are presented by applying a top-down, inside-out or bottom-up approach utilizing the Modeling Method Specification Framework in order to conceptualize, implement and deploy scenario-specific modeldriven design approaches that are either executed by machines or by humans. Focus of the paper is the common procedure to conceptualize Model-Driven Design for e-Applications.
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