FIG 1: Intracytoplasmic neuronal immunolabelling localised in the thalamic area of the brain by immunohistochemical detection using 3F4 monoclonal antibody (x 1000) FIG 2: Protease resistant prion protein (PrP res) demonstrated by Western blotting of samples from brains of cheetah (1, 2), sheep (3), cow (4) or BSE-infected mouse (5), with spongiform encephalopathy, using RS1 antiserum (2-5) or 3F4 monoclonal antibody (1)
Calcifying pseudoneoplasm or fibro-osseous lesion of the CNS is uncommon. We report a case in a 6-year-old boy who presented with generalized tonic-clonic seizures for 6 months. There was a calcified mass in the depth of the left temporal lobe, which on histology showed collagenous nodules surrounded by spindle cells and seperated by chondromyxoid matrix. The only other report of such a lesion in a child is of a 12-year-old boy with an epidural lesion at C-6 level. It is important to recognize this entity since it is slow growing with a good prognosis.
The present study was conducted with the aim to record the pathological conditions in the female genital tract of goats. A total of 660 female genital tracts of goats were collected randomly from various slaughter houses as well as from CIRG post-mortem house regardless of breed and age (3 months to 8 years old) of the animals. Out of total 660 samples collected and examined, 154 (23.32%) revealed different types of pathological conditions. Highest occurrence of pathological conditions was observed in the uterus (53.24%), followed by those in the ovary (25.97%), cervix (11.03%), fallopian tubes (5.19%) and vagina (4.54%). Endometritis (37/154; 24.02%) was the most common pathological lesion followed by ovarian cyst (22/154; 14.28%). Other pathological conditions included congenital anomalies (3/154; 1.94%), hydrosalpinx (2/154; 1.29%), cervicitis (10/154; 6.4%), vaginitis (3/154; 1.94%) etc. Abnormalities like ovarian tumour, hydrometra, retention of placenta and uterine pigmentations were also recorded.In this study thelesions that could result into infertility or sterility of the goats occurred in 12.7% ofther eproductive systems examined.
Development of goat spleen at various stages of gestation was studied. Primordium of spleen was observed on 46th day of gestation in close proximity to the developing rumen. All the parameters viz. length, width, thickness and weight were increased with advancement of age. Differentiating capsule and trabeculae were noticed on 69th day and 102th days of gestation, respectively. Reticular, collagen and elastic fibers were noticed at 60, 55 and 124 days of gestation, respectively. Red and white pulp was not fully differentiated till term.
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