Background: Sutures which are used for wound approximation can act as a reservoir of microbes at the surgical site leading to increased chances of surgical site infection (SSI). Sutures used in oral cavity are continuously bathed in saliva which results in wicking. Several studies on sutures treated with nanoparticles, antibacterial agent and various drugs to advance the therapeutical value of surgical sutures are in consideration, drug-eluting sutures has been notable in research to deliver localized effect on the site of incision. Ciprofloxacin and Aloe vera are routinely used agents in coating sutures. Aim: This study is to evaluate the antibacterial efficacy and oral biofilm inhibition of Ciprofloxacin and Aloe vera coated 3-0 silk sutures in comparison to uncoated sutures against E.coli. Material and Methods: Equal segments of ciprofloxacin and aloe vera coated 3-0 silk sutures are to be incubated in E.coli culture media (blood agar) at 37°C for 24 hours in aerobic atmosphere. Plain uncoated suture served as control. Assessment was done using Total Colony Forming Units and biofilm inhibition potential of sutures. Results awaited. Results: The zone of inhibition around ciprofloxacin coated suture is nearly double than that of with Aloe vera indicted that antibacterial efficacy of ciprofloxacin is more comparatively. No inhibition zone around uncoated plain 3-0 braided silk shows that it has no significant antibacterial activity. Conclusion: Within limitation of our study, it can be concluded that both ciprofloxacin and Aloe vera coated sutures have antibacterial property against gram negative E. coli and can have a promising role in prevention of SSI although it would require further in vivo validation.
Aim: This study is to evaluate in vitro the efficiency of Triclosan and Aloe Vera dentifrices in reducing the contamination of toothbrush bristles by a standard strain of E.coli after brushing. Settings and Design: Methods and Material: Nine Toothbrushes were divided, randomly, into 3 brushing groups, with 3 toothbrushes in each group (i.e) no dentifrice, dentifrice containing Aloe vera (Danthkanthi(R)) and dentifrice containing Triclosan (Colgate total(R)) An initial culture was made with the standard strain of E.coli(ATGC 25922) in a nutrient broth which was incubated. The dentifrices were distributed over the bristles with the tip cut from its handle and brushing was performed for 1 min on autoclaved teeth. The trimmed bristles of each toothbrush were stored in individual test tubes which were kept incubated at 37°C for 48 hrs. Streaking was done in Nutrient Agar medium kept incubated at 37°C for 24 h. The number of colony forming units was manually counted. Results: The number colony forming units is highest in the control group and the least in Triclosan containing dentifrice. Conclusions: It can be concluded that both Aloe vera and Triclosan can be used as dentifrices that help reduce E.coli count on toothbrushes.
Pyogenic granuloma or granuloma pyogenicum of oral cavity is a benign non-neoplastic mucocutaneous lesion evolving in response to local irritation, its a fairly common lesion comprising approximately 1.8% of a large series of oral biopsies. A clinically and histologically similar lesion restricted to gingiva occurs in 0.5% to 2.7% of pregnant females and is called granuloma gravidarum or "pregnancy tumor". 1,2 The unusual location of a pyogenic granuloma on midline of dorsum of the tongue in a pregnant patient prompted this case report.
According to the WHO Mental health is defined as a state of well-being in which every individual realizes his or her own potential, can cope with the normal stresses of life, can work productively and fruitfully, and is able to make a contribution to her or his community. One of the most obvious, yet under-recognised environmental factors in the development of major trends in mental health is the role of nutrition. The study is a qualitative analysis on one subject. The objective is to investigate the role of nutrition in the effective management of Attention-deficit/hyperactivity disorder (ADHD), as balanced nutrition is very important during childhood which is a period of vigorous growth, increased activity, and development of body functions and social cognitive abilities. The treatment implications of research into nutrition and mental health are enormous. Attention-deficit/hyperactivity disorder (ADHD) is one of the most commonly diagnosed chronic mental conditions of childhood. ADHD has a large genetic component to its etiology, and alterations in the noradrenergic and dopamine systems lead to dysfunction in higher cortical processing related to attention, alertness, and executive functions (e.g., planning, working memory, abstract reasoning, mental flexibility). According to extensive research conducted two food groups that have subsequently been implicated as having a considerable impact on ADHD are essential fatty acids and minerals. Their exists and inversely linear relationship between levels of EFA in the body and the degree of the disorder. A similar inverse relationship has been found with levels of iron in children and symptoms of ADHD, deficiencies in magnesium and zinc have also been noted.
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