We do not find any correlation between tumor stage or site and MUC1, MUC2 or MUC5AC expression. MUC1and MUC5AC expression showed significant correlation with tumor grade.
The objective of this study was to present an unusual case of isolated dystrophic calcification in masseter and the diagnostic challenge it posed. A case report on a 14-year-old boy presented with swelling in left parotid region along with the review of literature was reported. Histopathological and biochemical analyses of the excised mass diagnosed this affliction as dystrophic calcification. Dystrophic calcification is deposition of calcium salt in degenerated tissues in the presence of normal calcium and phosphorous metabolism. It usually occurs in injured tissues. This is different from systemic mineral imbalance causing metastatic calcification and needs to be differentiated. On reviewing the literature, this appears to be the second reported case in the world wide literature. The unique presentation, diagnosis, and surgical management of dystrophic calcification have been described.
Mammary analog secretory carcinoma (MASC) is a low-grade malignant tumor of salivary glands. It is so named because of its cytohistopahological, immunohistological, and cytogenetic resemblance to secretory carcinoma of the breast. Since the first description of this tumor in 2010, about 70 cases have been reported in literature. We report a case of this recently described tumor in a 21-year-old female. The radiological diagnosis of her parotid swelling was pleomorphic adenoma. The cytological evaluation was suggestive of oncocytoma. The histopathology showed a low-grade malignant neoplasm and the differential included papillary variant of acinic cell carcinoma, oncocytic variant of mucoepidermoid carcinoma, and MASC. Immunohistochemistry confirmed the diagnosis of MASC. We have included a brief review of literature.
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