A novel polysaccharide
structure (PS-T80) was collected from
Ophiocordyceps sobolifera
biomass and characterized via
a combination of chemical and spectral analyses. Employing high-performance
gel permeation chromatography (HPGPC), the average molecular weight
is proven to be 7.4 × 10
4
Da. Furthermore, a sugar
composition analysis of the obtained polysaccharide suggests two main
sugars, β-
d
-glucose and α-
d
-mannose,
at a molar ratio of 2:1, respectively, in the backbone. The structure
analysis unveils that PS-T80 is a mannoglucan, possessing the repeating
unit of [→3)-β-
d
-Glcp-(1 → 3)-α-
d
-Manp-(1 → 3)-β-
d
-Glcp-(1→]
n
. Such a configuration could be considered
a novel polysaccharide. Impressively,
in vitro
antioxidant
tests revealed that PS-T80 has a promising antioxidant activity. These
results demonstrate that the obtained PS is a potential bioactive
material for biomedical applications.
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