The biological mechanism that regulates the relationship between the thermal dose and the healing process of soft tissues with low or high water content or with low or high blood perfusion is still under study. Microwave diathermy treatment at 434 and 915 MHz can be effective in the short-term management of musculo-skeletal injuries.

We confirmed that radio-hyperthermia is useful in re-irradiation with a very high patient compliance.

The aim of the present study is to verify the knowledge of risks and complications of oral piercings, and to observe the main complications associated with piercings, using a sample from central Italy of patients wearing intraoral piercings. Through piercing and tattoo studios selected randomly in Rome, Latina and Campobasso, and a tattoo and piercing convention in Latina, a group of 387 individuals with oral piercings were selected and asked to complete an anonymous questionnaire. After filling in questionnaires, 70 individuals of the 387 selected agreed to be visited to allow the observation of the integrity of their teeth and gums (especially close to the oral piercing), oral hygiene conditions, piercing cleaning, bad habits and gingival recession. Among the respondents, 46.8% said they had not been informed about these risks, 48.5% claimed not to clean the piercing, 70.6% stated that they had not been made aware of gingival problems that can arise, 60.4% subjects stated that they were not informed about the complications of piercings concerning teeth, 52.8% had insufficient oral hygiene conditions, 42% showed signs of generalised gingivitis, 20% had 3–4 mm recessions and 22% had tooth fracture(s) due to piercing. From this study, it emerged that oral piercings can represent a risk to oral health and that there is a widespread lack of awareness of the complications and correct methods of maintaining oral piercings. Periodic checks by both dentists and dental hygienists, for patients with oral piercings, could play a decisive role in preventing, intercepting and treating the complications that they can cause.

3-(1H-Pyrrol-1-yl)-2-oxazolidinones 1aminus signi have been synthesized as pyrrole analogues of toloxatone (Humoryl), an antidepressant agent belonging to the 3-phenyl-2-oxazolidinone class, and their monoamine oxidase (MAO) type A and B inhibitory activities have been evaluated. The majority of 1aminus signi showed inhibitory activity against the A isoform of the enzyme higher than that exerted against the MAO-B, the sole exception being the (S)-5-aminomethylderivative 1d. (R)-5-Methoxymethyl-3-(1H-pyrrol-1-yl)-2-oxazolidinone 1b, the most potent among test derivatives, was 78-fold more potent than toloxatone.

Objective: To investigate the changes in temperature of human muscle during microwave hyperthermia. Methods: Skin surface and muscle temperatures were measured in 11 healthy adult men (mean (SD) age 24.3 (2.2) years; height 174.2 (6.1) cm; weight 70.0 (5.3) kg) during a 30 min exposure of the thigh to 434 MHz microwave hyperthermia. Skin temperature was maintained at the pilot temperature of 40˚C, and the temperature of the water in the bolus was 38˚C. The peak power output was set at 60 W and controlled automatically to maintain the pilot temperature. The temperature was measured in the vastus lateralis muscle at an average muscle depth of 2.0 (0.2) cm, using a 23 G Teflon-shielded thermocouple. Biopsy specimens were obtained for light microscopy from three subjects. A muscle-equivalent phantom was used to evaluate the vertical heating pattern. Results: Both skin and muscle temperatures increased from baseline, and muscle temperature was higher than skin temperature (skin temperature 39.2 (0.5)˚C, temperature rise 5.0 (1.5)˚C; muscle temperature 43.7 (0.8)˚C, temperature rise 8.9 (1.4)˚C). At the end of the hyperthermia treatment, muscle temperature decreased to 39.8 (0.9)˚C, but was still 4.8 (1.5)˚C higher than the baseline. No signs of muscle damage were observed on the basis of the blood creatine kinase activity and histological sections. Conclusions:The results show that the 434 MHz microwave hyperthermia treatment increased and maintained muscle temperature locally by 6.3-11.4˚C without muscle damage. These findings suggest that the microwave hyperthermia system provides effective and safe treatment. F or many years, heat treatment has been used as a therapy for muscle tissue injured in sports. There are several heating modalities, including silicon gel hot packs, whirlpools, paraffin baths, ultrasound and electromagnetic waves.

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“Scuola di base” è un’espressione utilizzata diffusamente per richiamare l’esigenza di una visione integrata dei primi segmenti di istruzione, a più riprese interessati da interventi di riforma e da processi di cambiamento. Ipotizzare scenari di trasformazione della scuola di base, nelle pratiche e nella normativa, significa assumere una prospettiva che connetta il tema dell’apprendimento, nelle sue diverse sfaccettature, alla dimensione organizzativa della scuola. Il volume giunge a trattare questioni relative alla scuola di base a partire da un perimetro più vasto, ovvero da domande di fondo sull’apprendere e l’insegnare, e attraverso l’esame del concetto di ambiente di apprendimento – costrutto a cui ricondurre l’insieme degli elementi che regolano lo svolgimento del processo di insegnamento/apprendimento – sviluppa riflessioni su… della scuola di base nella sua dimensione strategica, l’istituzione scolastica.

No abstract