Radio hyperthermia for re-treatment of superficial tumours

Gabriele, P.; Ferrara, Teresa; Baiotto, Barbara; Garibaldi, E.; Marini, Piergiorgio; Penduzzu, G.; Giovannini, Valentina; Bardati, F.; Guiot, Caterina

doi:10.1080/02656730802669593

Cited by 36 publications

(33 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dimensions were computed in the frequency range from 85 MHz to 200 MHz. Although there are some studies concerning applicators which works at 70 and 343 MHz (for deep and superficial hyperthermia, respectively), here we propose another frequency range [8,17]. These frequencies were proposed because it was necessary to find a compromise between aperture dimensions and penetration depth, which is limited by frequency.…”

Section: Rectangular Waveguide Design Theory and Aperture Reductionmentioning

confidence: 99%

See 1 more Smart Citation

Fem Modeling for Performance Evaluation of an Electromagnetic Oncology Deep Hyperthermia Applicator When Using Monopole, Inverted T, and Plate Antennas

Trujillo-Romero¹,

Salas²,

Vera³

2011

PIER

View full text Add to dashboard Cite

Abstract-This study focuses on the evaluation of the performance of a rectangular waveguide for deep hyperthermia when different antennas are used. Although there are several models of hyperthermia applicators, there are no studies of the advantages of employing different antennas for waveguides used in deep seated tumor treatments. Monopole antennas are the most used radiating elements inside waveguides. Here, the modeling of a monopole and two new proposed antennas, inverted T and plate, in order to find their optimal performance is presented. Parameters like output power, SWR and transmission coefficient generated for each modeled antenna were calculated by using the finite element method. The antennas with the best performance were selected in order to model an applicator-phantom system, which was used to calculate the temperature distributions generated inside the muscle phantom. The models were based on Maxwell and bioheat equations. Finally, thermal distributions were obtained and compared. The results indicate that the plate antenna generated a better focusing. The SWR obtained was 1.25, the output power was 54.71 W of 66 W applied, and the 42 • C isotherm had a size of 2 cm × 2 cm.

show abstract

Section: Rectangular Waveguide Design Theory and Aperture Reductionmentioning

confidence: 99%

“…The SWR is defined as the ratio of the maximum amplitude of the standing wave to the minimum amplitude. The SWR can be written as [17]:…”

Section: Fem Modeling: Characteristics Of the System And Validation Bmentioning

confidence: 99%

Fem Modeling for Performance Evaluation of an Electromagnetic Oncology Deep Hyperthermia Applicator When Using Monopole, Inverted T, and Plate Antennas

Trujillo-Romero¹,

Salas²,

Vera³

2011

PIER

View full text Add to dashboard Cite

show abstract

“…Adequate heating equipment is essential to realise an acceptable thermal dose. Both capacitive and electromagnetic radiative hyperthermia systems are used for superficial heating [8][9][10][11][12]. Capacitive systems are more often used in Asian countries, though also increasingly popular in the Western world.…”

Section: Introductionmentioning

confidence: 99%

A comparison of the heating characteristics of capacitive and radiative superficial hyperthermia

Kok

Crezee

2017

International Journal of Hyperthermia

View full text Add to dashboard Cite

Background: Superficial hyperthermia is applied in combination with radiotherapy for e.g. melanoma and recurrent breast cancer, using both capacitive and radiative systems. In this paper, numerical simulations are applied to address the question which technique yields the most favourable heating characteristics. Methods: A 434 MHz contact flexible microstrip applicator (CFMA type 4H, size 19.6 Â 19.6 cm 2 ) and a capacitive system consisting of two circular electrodes with diameter 15 and 25 cm were modelled. The water bolus of the CFMA was filled with deionised water and for capacitive heating both saline and deionised water were modelled. Specific absorption rate (SAR) and temperature simulations were performed for a perfused muscle-equivalent phantom and phantoms with a 1 cm thick superficial fat layer, assuming cylindrical target regions. Subsequently, a real patient model with a chest wall recurrence was studied with the target assumed to have muscle-like properties, fat properties or heterogeneous properties as derived from the CT Hounsfield Units. Results: Phantom simulations showed that high SAR peaks occur around the bolus edges with capacitive heating. Power absorption below the fat layer is substantially higher for radiative heating and unless the target region is limited to the fat layer, radiative heating yields better target coverage in terms of SAR and temperature. Patient simulations showed that the T 90 for radiative heating was 0.4-1.1 C higher compared with capacitive heating. Conclusions: Radiative heating yields more favourable SAR and temperature distributions for superficial tumours, compared with capacitive heating, especially within heterogeneous tissues. Higher tumour temperatures are achieved without occurrence of treatment limiting hot spots.

show abstract

“…Gabriele et al [35] based on their experience with the application of hyperthermia in conjunction with radiotherapy proposed that RTHT may be the treatment of choice for superficial recurrences. In their study the efficacy of RTHT was evaluated for patients that had been previously irradiated and had relapsed.…”

Section: Resultsmentioning

confidence: 99%

Hyperthermia Is Now Included in the NCCN Clinical Practice Guidelines for Breast Cancer Recurrences: An Analysis of Existing Data

et al. 2015

View full text Add to dashboard Cite

Background: Hyperthermia has been included in the 2013 National Comprehensive Cancer Network (NCCN) guidelines as an option for the treatment of breast recurrences. The purpose of this article is to demonstrate the important role of hyperthermia as a therapeutic modality by presenting clinical trials on this subject carried out in the last decades. Materials and Methods: All relevant trials published since 1987 were retrieved from Medline and reviewed. Results: Results show that the addition of hyperthermia to radiotherapy and/or chemotherapy for the treatment of breast cancer enhances treatment response and can increase local control. Conclusion: Further studies are required to evaluate potential benefits of hyperthermia in the treatment of other kinds of superficial tumors.

show abstract

Radio hyperthermia for re-treatment of superficial tumours

Abstract: We confirmed that radio-hyperthermia is useful in re-irradiation with a very high patient compliance.

Cited by 36 publications

References 41 publications

Fem Modeling for Performance Evaluation of an Electromagnetic Oncology Deep Hyperthermia Applicator When Using Monopole, Inverted T, and Plate Antennas

Fem Modeling for Performance Evaluation of an Electromagnetic Oncology Deep Hyperthermia Applicator When Using Monopole, Inverted T, and Plate Antennas

A comparison of the heating characteristics of capacitive and radiative superficial hyperthermia

Hyperthermia Is Now Included in the NCCN Clinical Practice Guidelines for Breast Cancer Recurrences: An Analysis of Existing Data

Contact Info

Product

Resources

About