We deduce and study an analytical expression for Fresnel diffraction of a plane wave by a spiral phase plate (SPP) that imparts an arbitrary-order phase singularity on the light field. Estimates for the optical vortex radius that depends on the singularity's integer order n (also termed topological charge, or order of the dislocation) have been derived. The near-zero vortex intensity is shown to be proportional to rho2n, where p is the radial coordinate. Also, an analytical expression for Fresnel diffraction of the Gaussian beam by a SPP with nth-order singularity is analyzed. The far-field intensity distribution is derived. The radius of maximal intensity is shown to depend on the singularity number. The behavior of the Gaussian beam intensity after a SPP with second-order singularity (n = 2) is studied in more detail. The parameters of the light beams generated numerically with the Fresnel transform and via analytical formulas are in good agreement. In addition, the light fields with first- and second-order singularities were generated by a 32-level SPP fabricated on the resist by use of the electron-beam lithography technique.

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A new family of paraxial laser beams that form an orthogonal basis is discussed. When propagated in uniform space, these beams preserve their structure to scale. The intensity distribution profile for such beams is similar to that for the Bessel modes, representing a set of alternating bright and dark concentric rings. The complex amplitude of these beams is proportional to the degenerate (confluent) hypergeometric function, and therefore we term such beams hypergeometric (HyG) modes. The HyG modes are generated with a liquid-crystal microdisplay.

We propose a new, three-parameter family of diffraction-free asymmetric elegant Bessel modes (aB-modes) with an integer and fractional orbital angular momentum (OAM). The aB-modes are described by the nth-order Bessel function of the first kind with complex argument. The asymmetry degree of the nonparaxial aB-mode is shown to depend on a real parameter c≥0: when c=0, the aB-mode is identical to a conventional radially symmetric Bessel mode; with increasing c, the aB-mode starts to acquire a crescent form, getting stretched along the vertical axis and shifted along the horizontal axis for c≫1. On the horizontal axis, the aB-modes have a denumerable number of isolated intensity zeros that generate optical vortices with a unit topological charge of opposite sign on opposite sides of 0. At different values of the parameter c, the intensity zeros change their location on the horizontal axis, thus changing the beam's OAM. An isolated intensity zero on the optical axis generates an optical vortex with topological charge n. The OAM per photon of an aB-mode depends near-linearly on c, being equal to ℏ(n+cI1(2c)/I0(2c)), where ℏ is the Planck constant and In(x) is a modified Bessel function.

We derive analytical expressions containing a hypergeometric function to describe the Fresnel and Fraunhofer diffraction of a plane wave of circular and ringlike cross section by a spiral phase plate (SPP) of an arbitrary integer order. Experimental diffraction patterns generated by an SPP fabricated in resist through direct e-beam writing are in good agreement with the theoretical intensity distribution.

We obtain analytical expressions for the complex amplitudes of optical vortices deformed by astigmatic transforms, i.e., passed either through a cylindrical lens or through an inclined spherical lens. We also obtain similar analytical expressions describing propagation of an optical vortex generated when a Gaussian beam illuminates an inclined spiral phase plate (SPP) or when an elliptic Gaussian beam illuminates a SPP (not inclined). All these optical vortices with a topological charge (TC) n are described by the n-th order Hermite polynomial with a complex argument. It is shown that the argument is real only on a straight line in the transverse plane of the laser beam. There are n intensity nulls on this line. The treated here astigmatic transforms are used to determine the integer TC of optical vortices. We conduct a comparative experimental study of different astigmatic transforms and we show that the transform with a cylindrical lens is the best for determining the TC. Unlike other similar works, in this study we achieve transformation of n-degenerate intensity null of an optical vortex with the TC n=100 into n isolated first-order intensity nulls.

Delirium is a neuropsychiatric syndrome characterized by impairment of consciousness, changes in cognition, or perceptual disturbances. In addition, delirium is often accompanied by delusions, hallucinations, and agitation. In this study, 12 older patients with delirium were treated for neuropsychiatric symptoms with quetiapine. The mean duration for stabilization was 5.91 +/- 2.22 days, and the mean dose was 93.75 +/- 23.31 mg/day. None of the 12 patients developed extrapyramidal symptoms. There were significant improvements on all measures used in this study. Interestingly, the Delirium Rating Scale scores along with scores of the Mini-Mental State Examination and Clock Drawing Test continued to improve throughout the 3-month study period. In our study, we found that quetiapine was a safe and effective treatment in hospitalized older patients with delirium.

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