The work aimed to evaluate the effectiveness of the developed distraction system based on the rod external monolateral fixation mechanisms by comparing it with the classical technique of long tubular bones distraction based on the circular multi-axial system. The study included patients with a genetically confirmed diagnosis of achondroplasia. The experimental group consisted of 14 patients who underwent surgical limb lengthening by the rod monolateral external fixator with a distraction system developed by the authors. The lengthening was performed on 28 segments of tubular bones. The majority of the experimental group patients achieved the lengthening value close to the planned one and the deformation correction. The fixation period was averagely 83.8 ± 3.7 days, the regenerate length was 8.5 ± 0.6 cm, and the mechanical strength of the distraction regenerate was 10.3° ± 2.18°. The rod external fixator with a control distraction system developed by the authors has small dimensions and low weight of the external supporting elements of high durability. It is reported to provide a good psychological tolerance of the treatment process and significantly outperforms the circular multi-axis system. Considering the aforementioned, the proposed apparatus can grant good orthopedic care to patients with achondroplasia.
AIM:The purpose of the current article is to study the state of the intestinal microflora in the context of chronic colonic stasis and assesses the methods of its correction by means of siphon enema and probiotics' implication (bifidumbacterin and lactobacterin) to prevent the development of HAEC. METHODS:This study was conducted in the Astana City Children's Hospital No. 2 and involved 60 children who applied for medical help with symptoms of chronic constipation. They were admitted to the hospital in a planned or emergency manner with suspected Hirschsprung's disease in the period from 2015 to 2017, after approval of the Ethics Committee. An X-ray contrast study of the large intestine (irrigography) was performed in all the children for a diagnostic purpose. The following parameters of the state of the large intestine were studied: The function of the ileocecal valve (Bauhin's valve), the diameter and shape of the large intestine, the presence of pathological formations, and symptoms of intestinal obstruction. Statistical analysis was carried out using Student's test for dependent and independent samples by means of the BioStat Software. RESULTS:After treatment, the bacteriological examination of stool samples demonstrated an increase in the number of beneficial microorganisms and a decrease in the number of opportunistic microorganisms. The growth in the number of patients with the normal intestinal microflora (14 patients -70%) was observed along with the reduction in the number of patients with intestinal dysbiosis, with a statistically significant difference (p < 0.001). CONCLUSION:The developed method of correcting the quantitative composition of the intestinal microflora is very effective and can be implemented in clinical practice.
Objective: The problem of chronic colostasis is especially relevant in children. Numerous research studies have been devoted to this type of pathology, but until now, no final solution has been proposed both in traditional therapy and surgical treatment. The research aimed to study the state of intestinal microbiota in children with chronic colostasis in preparation for irrigation and to evaluate the combined method of its correction by oral and rectal probiotic administration. Materials and methods: The study enrolled 100 patients of both genders aged 5-15 years with the diagnosis of chronic colostasis. All patients were divided into main and control groups consisting of 50 people in each one. For the correction of intestine microbiota, the probiotics in the main group were administered orally and using enema with direct irrigation of the large intestine cavity after preparation for X-ray analysis, while patients of the control group received probiotics only orally. Results and Discussion:In the main group, the concentration of all types of useful microorganisms in the intestine increased to normal values after the correction, the number of useful microorganisms is statistically significantly higher, and the number of opportunistic enterobacteria is less in comparison with the those in the control group (p<0.001). Conclusion:The developed method of combined application of probiotics orally and introduction into the lumen of the large intestine with an enema is an effective way to correct the quantitative composition of intestinal microbiota at chronic colostasis in children. Bangladesh Journal of Medical Science Vol. 22 No. 01 January’23 Page : 180-188
AIM: The purpose of the current article is to study the state of the intestinal microflora in the context of chronic colonic stasis and assesses the methods of its correction by means of siphon enema and probiotics’ implication (bifidumbacterin and lactobacterin) to prevent the development of HAEC. METHODS: This study was conducted in the Astana City Children’s Hospital No. 2 and involved 60 children who applied for medical help with symptoms of chronic constipation. They were admitted to the hospital in a planned or emergency manner with suspected Hirschsprung’s disease in the period from 2015 to 2017, after approval of the Ethics Committee. An X-ray contrast study of the large intestine (irrigography) was performed in all the children for a diagnostic purpose. The following parameters of the state of the large intestine were studied: The function of the ileocecal valve (Bauhin’s valve), the diameter and shape of the large intestine, the presence of pathological formations, and symptoms of intestinal obstruction. Statistical analysis was carried out using Student’s test for dependent and independent samples by means of the BioStat Software. RESULTS: After treatment, the bacteriological examination of stool samples demonstrated an increase in the number of beneficial microorganisms and a decrease in the number of opportunistic microorganisms. The growth in the number of patients with the normal intestinal microflora (14 patients – 70%) was observed along with the reduction in the number of patients with intestinal dysbiosis, with a statistically significant difference (p < 0.001). CONCLUSION: The developed method of correcting the quantitative composition of the intestinal microflora is very effective and can be implemented in clinical practice.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.