Evaluating the results of long tubular bone distraction with an advanced rod monolateral external fixator for achondroplasia

Abstract

The work aimed to evaluate the effectiveness of the developed distraction system based on the rod external monolateral fixation mechanisms by comparing it with the classical technique of long tubular bones distraction based on the circular multi-axial system. The study included patients with a genetically confirmed diagnosis of achondroplasia. The experimental group consisted of 14 patients who underwent surgical limb lengthening by the rod monolateral external fixator with a distraction system developed by the authors. The lengthening was performed on 28 segments of tubular bones. The majority of the experimental group patients achieved the lengthening value close to the planned one and the deformation correction. The fixation period was averagely 83.8 ± 3.7 days, the regenerate length was 8.5 ± 0.6 cm, and the mechanical strength of the distraction regenerate was 10.3° ± 2.18°. The rod external fixator with a control distraction system developed by the authors has small dimensions and low weight of the external supporting elements of high durability. It is reported to provide a good psychological tolerance of the treatment process and significantly outperforms the circular multi-axis system. Considering the aforementioned, the proposed apparatus can grant good orthopedic care to patients with achondroplasia.

Quality of Life in Children With Achondroplasia Undergoing Paired Limb Lengthening With an External Fixator and Modified Distraction Control: Observational Nonrandomized Study

“…Currently, transosseous distraction osteosynthesis is prioritized in orthopedic care [ 9 , 10 ]. This method is based on the general biological property of tissues to respond by regeneration to dosed stretching [ 11 ]. The conventional approach for uniform tubular bone lengthening typically involves 1 mm per day in 0.25 mm fractions across 4 sessions [ 12 ].…”

“…Their straightforward assembly and mounting on the limb segment can help significantly reduce surgery duration, which is important in paired limb lengthening [ 21 ]. The authors developed a bar external fixation device with a distraction control system that showed better results than the circular multiaxial system regarding fixation time, regenerative length, deformation angles, pain intensity indexes, and complication rates [ 11 ]. This study aims to compare the quality of life (focusing on postoperative pain syndrome, physical activity, and emotional state) of children with achondroplasia undergoing paired limb lengthening using 2 different methods: an external fixator with modified distraction control and a circular multiaxial system developed by the authors.…”

Prevalence of thalassemia in the Vietnamese population and building a clinical decision support system for prenatal screening for thalassemia

“…Nowadays, modern technology has been researched and applied in the field of medicine to support doctors in patient care as well as practice specialize [15]. A clinical decision support system (CDSS) is "any electronic or non-electronic system designed to aid directly in clinical decision making in which characteristics of individual patients are used to generate patient-specific assessments or recommendations that are then presented to clinicians for consideration" [16].…”

Prevalence of Thalassemia in the Vietnamese Population and Building a Clinical Decision Support System for Prenatal Screening for Thalassemia

“…Nowadays, modern technology has been researched and applied in medicine to support doctors in patient care and practice specialization. 15 A Clinical Decision Support System (CDSS) is "any electronic or non-electronic system designed to aid directly in clinical decision making, in which characteristics of individual patients are used to generate patient-specific assessments or recommendations that are then presented to clinicians for consideration". 16 CDSSs are classified as expert knowledge-based systems and artificial intelligence (AI).…”