P=0.001] compared with individuals who were never exposed to tobacco smoking. There were no differences across groups regarding cSLEDAI-2K scores.In multivariable linear regression models, obesity and current tobacco smoking were independently associated with lower EQ-5D-3L index scores (b=-0.12; P=0.021 and b=-0.11; P=0.029, respectively), and higher VAS fatigue (b=12.8; P=0.007 and b=17.5; P<0.001), VAS pain (b=12.1; P=0.004 and b=15.5; P<0.001), VAS well-being (b=9.6; P=0.028 and b=9.8; P=0.035) and HAQ scores (b=0.30; P=0.001 and b=0.27; P=0.007), but not with cSLEDAI-2K (b=-0.73; P=0.189 and b=0.34; P=0.572). Conclusions In a Swedish SLE population, obesity and tobacco smoking were independently associated with worse outcomescompared with normal weight patients and individuals who never smoked, respectively -regarding HRQoL, fatigue, pain and functional disability but not with clinical disease activity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.