PO.7.148 Patients with systemic lupus erythematosus and their experience with vaccination against COVID-19: a descriptive and explanatory study

Abstract

P=0.001] compared with individuals who were never exposed to tobacco smoking. There were no differences across groups regarding cSLEDAI-2K scores.In multivariable linear regression models, obesity and current tobacco smoking were independently associated with lower EQ-5D-3L index scores (b=-0.12; P=0.021 and b=-0.11; P=0.029, respectively), and higher VAS fatigue (b=12.8; P=0.007 and b=17.5; P<0.001), VAS pain (b=12.1; P=0.004 and b=15.5; P<0.001), VAS well-being (b=9.6; P=0.028 and b=9.8; P=0.035) and HAQ scores (b=0.30; P=0.001 and b=0.27; P=0.007), but not with cSLEDAI-2K (b=-0.73; P=0.189 and b=0.34; P=0.572). Conclusions In a Swedish SLE population, obesity and tobacco smoking were independently associated with worse outcomescompared with normal weight patients and individuals who never smoked, respectively -regarding HRQoL, fatigue, pain and functional disability but not with clinical disease activity.