in Wiley Online Library (wileyonlinelibrary.com).Rapid and efficient one-pot three-component synthesis of new spironaphthopyrano-one derivatives by cyclocondensation reaction in aqueous media is achieved under microwave irradiation conditions. This protocol has the advantages of higher yield, lower cost, reduced time, environmental impact, and convenient procedure.
A new and facile one‐pot method for synthesis of the title scaffolds is presented and further extended by employing two other reactive ketones instead of isatin.
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