Objective: assessing pharmacopuncture effect on pain syndrome and level of anxiety-depressive disorders in patients with chronic tension-type headache (CTTH).
Materials and methods. An open-label controlled trial was conducted on 95 CTTH patients split among two groups by means of adaptive randomization. The comparison group subjects were receiving 35-70 mg/day of amitriptyline and 450 mg/day of tolperisone, while patients of the treatment group were assigned 2-4 courses of pharmacopuncture by the original method. The results were evaluated on the basis of the scores obtained via Visual Analogue Scale (VAS), McGill Pain Questionnaire, Beck Depression Inventory (BDI), and State-Trait Anxiety Inventory (STAI) sensu Ch. Spielberger and Yu. Khanin.
Results. Patients in both clinical groups were inclined to a positive evaluation of received treatment. Based on the results of McGill Pain Questionnaire, we determined both affective and sensory pain descriptors, with a predominance of the latter. Both groups exhibited moderate depressive symptoms according to BDI of the psychological status. Prevalence of trait anxiety over reactive anxiety was determined by STAI. According to VAS, pain intensity after the treatment declined from 5.26±0.87 to 1.7±0.78 points (p<0.05) and from 5.17±0.78 to 1.65±0.79 (p<0.05) in the comparison group versus the treatment group. An improvement of anxiety and depression indicators was detected.
Conclusion. Our results have demonstrated that pharmacopuncture is very promising in treating CTTH patients
Objective: to study the formation of neurovascular conflicts of two types in patients with classical trigeminal neuralgia, depending on the influence of the environment of the Rostov region.Materials and methods: a retrospective study of the features of neurovascular conflict was conducted in 175 patients from the Rostov region who suffered from classical trigeminal neuralgia. The diagnosis of a variant of neurovascular conflict was carried out using spiral computed tomography on the device «Philips Ingenuity Core 128» The variant of neurovascular conflict was verified intraoperatively, when performing microvascular decompression of the trigeminal nerve root.Results: neurovascular conflict, both of the first and second types, occurs twice as often in women as in men. The development of the adhesive process in the zone of neurovascular conflict, which brings the root even closer to the artery that injures it, is due to the duration of the pathological process, during which inflammatory diseases of the paranasal sinuses, carious teeth, persistent herpesvirus infection play a significant role.Conclusions: variants of the syntopia of the trigeminal nerve root with the superior cerebellar artery in neurovascular conflict do not depend on environmental factors, and the frequency of occurrence of one type or another, as well as the gender ratio, correspond to the population.
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