Introduction: Osteoporosis is a worldwide public health problem that affects both male and females. It is a silent progressive disorder that affects the skeletal system and leads to diminished bone density and fracture. Therefore, awareness, attitude, and practices of people about osteoporosis contribute significantly to primary prevention and early detection of disease.
Objective: the present study conducted to assess the knowledge of the female medical students at King Faisal University about osteoporosis in Saudi Arabia.
Study design: A cross-sectional study conducted at the medical college of King Faisal University at Al-Ahsa region, Saudi Arabia. The study included all female medical students at King Faisal University, through an online self-administered questionnaire using the Osteoporosis Knowledge Assessment Tool (OKAT) questionnaire.
Results: The total number of participants was 176 female medical students, with 58.7% response rate. The age of participants ranged between 17 and 27 years, with a mean and standard deviation of 21.46±1.54 years. The participant's knowledge score about osteoporosis was as follow: 65.1% had satisfactory knowledge, 32.2% had poor knowledge, and only 2.3% of the participant had good knowledge.
Conclusion: Most of the participants had a satisfactory knowledge score on osteoporosis. However, there was a significant gap in knowledge regarding the risk factors such as high salt intake. The good knowledge score was significantly low in the present study compared to worldwide. Therefore, an educational effort is needed to improve knowledge and the quality and reliability of information about osteoporosis targeted undergraduates and young females in Saudi Arabia.
&-b3. Withinsubject comparison of the OKS and VASpain between time-points was made using repeat measure statistical tests. P<0.05 was considered statistically significant. The repeatability of matched SF measurements between time points was assessed for each analyte using the coefficient of variation (CV), and intraclass correlation coefficient for absolute agreement (ICC). The acceptable threshold for the interval CV (iCV) was set at 20%, which is the threshold for acceptable intra-and inter-assay precision. An ICC between 0.70-0.80 was considered strong absolute agreement and ICC >0.80 was considered excellent absolute agreement. Results: The median interval between SF measurements was 16.5 days (IQR 11.25-25). There was no significant within-subject difference in OKS or VAS pain between time-points. There were no significant clinical or radiographic differences between the Study and Reference groups. Only 10 analytes were >LOQ in all patient samples to allow meaningful analysis: 4 pro-inflammatory cytokines (IL6, IL8, IL12 & IL15); 3 chemokines (Eotaxin, MCP1 & IP10); and the 3 isoforms of TGF-b. The median iCV was <15% for all analytes and was significantly less than 20% for all analytes (p<0.05, one sample Wilcoxon signed rank test). The ICC was >0.88 for all analytes but one (TGF-b2, ICC¼0.75). For measurements
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