Introduction: Urinary bladder cancers are heterogeneous diseases consisting of a divergent group of tumors. Diseases of the urinary bladder, both neoplastic and nonneoplastic contribute to notable mortality and morbidity. Histopathology remains the gold standard of diagnosis. Bladder transurethral resection of the tumor is a therapeutic procedure that ensures the material necessary for histopathological diagnosis because it allows assessment of the degree of differentiation, depth of tumor invasion, parameters useful in the elaboration of diagnosis and prognosis assessment Material and Methods: All the urinary bladder biopsies submitted in the pathology laboratory during 1 year time period were included in the study. Results: Among the 51 total cases in the study, the male to female ratio was 4.67:1 with the age group of 22-96 years. Among the study population, 30 (52.7%) presented with hematuria, 10 (19.2%) with burning micturition, frequent urination, and lower abdominal pain. In the study, 44 (86%) showed neoplastic lesions while 7(14%) remaining were non-neoplastic lesions. Infiltrative urothelial carcinoma with low and high grades was diagnosed in 23% (12/51) Conclusions: This study has revealed that neoplastic lesions are more common than non-neoplastic lesions. A great majority of neoplastic lesions are of urothelial origin. Majority of which are invasive urothelial neoplasm. All urothelial neoplasms are more common in males. Cystoscopic studies and biopsies help in the early detection of bladder neoplasms and they form the mainstay of the diagnosis and follow-up.
The results for laparoscopic donor nephrectomy were comparable to those for open donor nephrectomy, and its acceptability was high. Laparoscopic donor nephrectomy should be the preferred approach for procuring the kidney graft.
Eosinophilic ureteritis is a rare cause of ureteric stricture causing hydroureteronephrosis. The exact aetiology of this condition is still unknown. This condition has been described in relation to atopy, hypereosinophilic syndrome and prior ureteral interventions. The histopathology is the conclusive diagnostic modality. The surgical resection of the ureteric stricture part with end-to-end anastomosis is usually successful. Herein, we report a case of a 19-year-old woman, who presented with right flank pain. With imaging and diagnostic ureteroscopy, the case was diagnosed as eosinophilic ureteritis. The case was successfully managed with resection of the stenosing part and end-to-end anastomosis. No cases of the disease have been reported until now in Nepal.
Objective of the Study: We sought to evaluate the role of guidewire placement as ureteral stent in passive ureteral dilatation for uretero-renoscope negotiation in pediatric patients. Study Designs: This was a prospective cross-sectional study. Place and Duration of the Study: Department of Urology, Manmohan Memorial Medical College and Teaching Hospital, Kathmandu, Nepal, (December 2019 to November 2020). Methodology: All pediatric patients (<18 years) diagnosed with more than 6mm size of distal ureter stone undergoing ureteroscopic lithotripsy under general anesthesia in which ureteroscope (4.5/6.5 Fr) negotiation and double J (DJ) ureteral stent (4 Fr) insertion could not be successful in first sitting were selected for the study. Data collection included demographics, clinical parameters, and perioperative and postoperative complications of those patients undergoing preoperative ureteral stenting with guidewire for 2 weeks for ureteroscopic management of ureteric stone after removal of guidewire. The statistical analysis of data was done using Microsoft Excel. Results: A total of 12 (41 %) cases underwent passive dilatation of ureter with guidewire. The mean age of the patients and mean stone size were 8.42 ± 1.7 years and 6.1 ±0.65mm respectively. None of the patients developed intraoperative and postoperative complications related to the procedure. Conclusion: Guidewire placement as ureteral stent for 2 weeks would result sufficient passive ureteral dilatation for the ureteroscope negotiation without any complication. PUD with guidewire is safe and effective. Additional research is necessary to determine whether the findings will be similar or not.
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