Oral submucous fibrosis (OSMF) is a well-established precancerous condition affecting the oral mucosa. Objective: To explore serum C- reactive protein levels in healthy patients and their comparison with diagnosed patients having oral submucous fibrosis. Methods: Eighty-two patients of all age groups, irrespective of gender and clinically diagnosed with oral submucous fibrosis, without any other systemic problem were included in the study. Patients were divided into two groups i.e., Group A = normal healthy patients and Group B = clinically diagnosed oral submucous fibrosis patients. After taking detailed history of patients of both groups, blood samples were collected from all patients for C- reactive protein levels. Results: Out of 82 patients, male were 30 (73.2%) and 34 (82.9%) and female were 11 (26.8%) and 7 (17.1%) with mean age of 41.0 ± 6.6 years and 42.6 ± 7.4 years in group I (normal healthy patients) and group II (oral submucous fibrosis patients) respectively. All patients were long-term consumers of betel quid with or without tobacco [13 (31.7%) and 28 (68.3%)], whereas no healthy patient was using betel quid. CRP level was significantly high 3.62 ±1.02 mg/dl in OSMF patients as compared to normal healthy patients 0.40 ± 0.21mg/dl. Similarly, CRP level was significantly abnormal (raised) in all OSMF patients as compared to normal healthy patients where only 7 (17.1%) were reported with abnormal (raised) CRP levels. Conclusions: Serum C- reactive protein levels in oral submucous fibrosis patients were significantly high as compared to normal healthy patients.
One of the most prevalent conditions affecting the oral mucosa is recurrent aphthous stomatitis (RAS), which is characterized by uncomfortable ulcerations on the movable or non-keratinized oral mucosa. Objective: To compare mean platelet volume (MPV) in patients of recurrent aphthous stomatitis (RAS) versus healthy control. Methods: This non-probability sampling case-control research included 56 RAS patients and 56 healthy controls. Patients who presented for dental treatment and have RAS in oral cavity were included. Patients with systemic inflammatory illnesses, autoimmune diseases like pemphigus, or infectious diseases like herpes who attended for dental treatment and exhibited RAS in the oral cavity were excluded. The healthy control group had no mouth ulcers or blood problems. A Student t-test compared MPV between cases and controls based on age, gender, and MPV. Results: The mean age of the participants was 29.35 ± 8.28 years, with 57 (50.89%) females and 55 (49.11%) males. The mean MPV in the RAS group (8.86 ± 0.33) was significantly higher (p < 0.001) than in the control group (6.95 ± 0.2). The univariable model coefficient of 1.91 (95% CI = 1.81-2.01, p < 0.001) indicates that the RAS group had a significantly higher MPV than the Control group. For gender, males had a lower MPV compared to females (β = -0.36), but it was not statistically significant (p = 0.056). Conclusions: RAS patients have higher platelet activity indicated by higher mean platelet volume (MPV) than healthy controls.
Background and Aim: Majority of the dentists gain hands on experience in managing dental traumas after entering into the field practically leading to an overall limited exposure to dental trauma injuries before their graduation time. The present study aimed to assess the dental student’s perception regarding simulation based dental trauma training. Materials and Methods: This comparative cross-sectional study involved 80 dentistry students at a Tertiary Care teaching institute of Lahore, Pakistan. A questionnaire based survey was done on final year dentistry students to answer the questions regarding their experience of simulated trauma splinting. Prior to this simulation-based practice, all participants were given a 60-minute lecture on oral trauma damage, followed by post-training questions. All the students completed simulated treatment using orthodontic wire, twist flex wire, nylon fishing line, and powermesh as splints. The glass ionomer cement and composite resin were bonding materials used. A 5-point Likert scale was used for post-training questions and answers. Results: Out of the 80 dental students, there were 46 (57.5%) male and 34 (42.5%) female students. The incidence of students who agreed and strongly agreed to their learning assisted by simulated trauma practice were 46.3% (n=37) and 33.8% (n=27) respectively.
Objective: To compare the outcomes in patients with single versus two miniplates for condylar fracture. Study Design: Cross-Sectional Study Place and Duration of Study: The study took place in Department of Oral & Maxillofacial Surgery, Institute of Dentistry LUMHS, Jamshoro. The duration of study was 6 months after the approval of the synopsis. Methodology: 40 people in all were included in the trial. A single miniplate was used for Group A's treatment, whereas two miniplates were used for Group B's treatment. Clinical assessment, orthopantomogram (OPG), a P.A. image of the face, and, if necessary, a 3D CT scan will be used to make the diagnosis of condylar fracture.The data was analysed by SPSS version 21 Results: Results of this investigation indicated that the preoperative evaluation of the variables including malocclusion, mouth opening, protrusive movement, and lateral movement revealed greater values, but much less means were found in postoperative examination. ANOVA is done one method to compare the means between preoperative and postoperative malocclusion. The statistical comparison is significant at less than 5%. The examination of platform fracture or bending occurs after the operation, which demonstrates that 92.5% of the population without platform fracture, while 7.5% exhibit platform fracture after surgery. Conclusion: In conclusion, it is indicated that two miniplates with less complicated fixing are superior to a single miniplate. Keywords: condylar fracture, single miniplates, double miniplate, treatment of condylar fracture, post-operative outcomes of condylar fracture.
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