Mucositis (sometimes referred to as stomatitis) is a condition of inflammation and deterioration of the mucous membrane lining of the gastrointestinal tract and oral cavity. [1] It is almost an inevitable after the effect of high-dose radiation therapy. The major determining factor, whether oral mucosa or gastric mucosa will be affected, is the cancer treatment regimen that is being employed. Apart from being caused by chemotherapy (CT) and radiotherapy (RT), mucositis can also occur in people receiving bone marrow transplants (BMTs). [2]
LIterature Search MethodoLogyAn electronic search was performed, from January 1990 to December 2018, to identify articles on the treatment and prevention protocols for CT-and RT-induced oral mucositis (OM). Related articles published in the English language and prominent oncology as well as dentistry journals were included.
Oral health is a cardinal element of nutritional as well as systemic well-being and plays a substantial part in sustaining optimum general health condition. Various factors influence oral health including metabolic diseases such as endocrine (diabetes mellitus [DM]), hematological, gastrointestinal, cutaneous, and neurological diseases. The intent of this review is to accentuate the correlation between DM and oral disorders, like those upsetting oral mucosa and supporting tissues. A review of literature was performed using relevant key words (“Oral Manifestations of Diabetes” OR “Oral Complications of Diabetes” OR “Oral Impacts of Diabetes” OR “Oral Repercussions of Diabetes“) in prominent journals pertaining to Endocrinology and Dentistry (Journal of Periodontology, Periodontology 2000, British Dental Journal, The Lancet Diabetes and Endocrinology, PloS ONE, and Nature Reviews Genetics). The most frequently witnessed diabetic manifestations in oral cavity include gingivitis and periodontitis leading to premature tooth loss, salivary dysfunctions, dental caries, delayed wound healing, bacterial and fungal infections, lichen planus, taste impairment, tongue abnormalities, neurosensory oral disorders, halitosis, and dry socket. In the end, I have comprehensively described the role of antidiabetic drugs in the management of DM and eventually leading to prevention of its oral complications. In this review, etiopathophysiology of each oral complication has been prudently analyzed to contemplate the establishment of a possible preventive and treatment approach.
<p>The purpose of this study was to investigate the anti-diabetic effect of crude <em>Pistacia lentiscus</em> gum (mastic gum) in alloxan-treated diabetic rat model. The crude <em>P. lentiscus</em> (100 mg/kg) showed significant (p<0.001) reduction in blood glucose as compared to control. Liver function test also showed significant changes (p<0.001) as compared to alloxan-treated group. The results of this study showed that crude <em>P. lentiscus</em> gum have considerable efficacy in curing diabetes and have hepatoprotective effect. </p><p> </p>
<p class="Abstract">The aim of this review is to report the medicinal plants which have anti- fibrotic effect characterized in different studies. They are summarized which include name of the plants, part used, liver fibrosis model, fraction of plant used and observations. The medicinal plants play an important role in treatment and prevention of liver fibrosis through different physiological mechanism. The effects of medicinal plant may delay the development of liver fibrosis and have potential to reverse or degrade the accumulation of extra cellular matrix. Four different databases are used and 18 plants are included which have the potential for reversal of liver fibrosis. There are also few more plants but they are not characterized well in literature.</p>
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