Aim: Peptic ulcer perforation (PUP) is currently the most common complication of peptic ulcer disease (PUD), which requires surgery. Mortality and morbidity rates are high after surgical treatment. The aim of this study was to determine the predictive factors affecting postoperative mortality in patients undergoing surgery due to peptic ulcer perforation.
Material and Method:The study included 135 patients diagnosed and operated on because of PUP in the general surgery clinic between February 2015 and January 2020. Evaluations were made of the relationships between mortality and age, gender, ASA scores, season of surgery, preoperative leukocyte, preoperative neutrophil to lymphocyte ratio (NLR), preoperative creatinine and amylase values, location and diameter of the perforation, comorbid diseases, onset of pain and time of surgery.Results: Advanced age, male gender, high ASA score, >12 hours between the onset of the symptoms and the time of surgery, and high creatinine, NLR and amylase values before surgery, ulcer diameter >1 cm and comorbid diseases were associated with mortality. No relationship was found between the location of the ulcer and leukocyte values at the time of admission and mortality.
Conclusion:Advanced age, male gender, high ASA score, >12 hours between the onset of symptoms and the time of surgery, and high preoperative creatinine, NLR and amylase values, ulcer diameter >1 cm and comorbid diseases are risk factors for mortality in peptic ulcer perforation. Understanding these factors, identifying patients at risk, and early intervention can help reduce mortality in PUP.
AİM
Staging laparoscopy enables us to perform palliative treatment, neo-adjuvant therapy for curative resection or direct curative resection and making a decision with minimal morbidity by avoiding from unnecessary laparotomies. In the present study, the importance of staging lapafoscopy was retrospectively investigated by using clinical and pathologic data.
METHODS
Data of 70 out of 350 patients who underwent diagnostic laparoscopy due to gastric cancer at Surgical Oncology department between August 2013 and January 2020 were retrospectively analyzed.
RESULTS
Peritoneal biopsy was positive for malignity in 41 (58.5%) and negative in 29 (41.5%) of the patients who underwent SL. Peritoneal cytology (PC) results were negative in 32 (45.7%) patients and positive in 38 (54.3%) patients. Peritoneal biopsy and cytology results were concurrently positive in 35 patients and concurrently negative in 26 patients.
CONCLUSİONS
In conclusion, even the most developed imaging methods cannot provide 100% staging, therefore SL plays an important role in treatment of gastric cancer and laparoscopic staging is essential as a simple, inexpensive, safe and well tolerated method in patients who have the suspicion of peritoneal disease and who cannot be clearly evaluated with pre-operative methods.
Introduction: The study aims to evaluate the long-term results of patients who underwent laparoscopic gastrectomy for gastric cancer in Ankara University Medical Faculty, Surgical Oncology Clinic, within 5 years. Materials and Methods: We retrospectively reviewed the data of patients who underwent laparoscopic gastrectomy for gastric cancer at the Surgical Oncology Clinic of Ankara University Medical Faculty between January 2014 and September 2019. One hundred forty-six patients were included in the study. Results: Fifty-one (34.9%) of the patients were female; 95 (65.1%) were male. The meanstandard deviation and median (minimum-maximum) values of the patients were 60.92-14.13 and 64.00 (22.00-93.00), respectively (Table 1). Eighty-seven (59.6%) cases were located in the antrum, 29 (19.9%) were in the cardia region, and 30 (20.5%) were in the corpus region. Overall, 106 (72.6%) of 146 patients were alive, while 40 (27.4%) were ex. The mean survival was 21.8 months (0-69). Postoperative mortality was seen in 9 patients (6.2%) and our disease-free survival rate was 70.5%. Recurrence occurred in 14 (9.6%) of all patients. Conclusion: In conclusion, although laparoscopic gastrectomy is a reliable and feasible method for gastric cancer, the standardization of laparoscopic surgery is required in clinics.
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