Latar Belakang. Anemia merupakan salah satu permasalahan gizi yang banyak terjadi di negara berkembang. Faktor gizi yang turut berkontribusi terhadap kejadian anemia diantaranya adalah kurangnya asupan zat gizi yang memengaruhi pembentukan Hemoglobin (Hb) pada penderita anemia. Tujuan. Penelitian ini bertujuan untuk mengetahui gambaran konsumsi energi, protein, zat besi, asam folat, vitamin C, vitamin A, dan seng pada subjek penderita anemia dibandingkan dengan angka kecukupan gizi (AKG) yang diduga menjadi faktor penyebab anemia. Metode. Penelitian ini menggunakan desain penelitian cross-sectional dan merupakan bagian dari penelitian “Observasi Klinik Formula Jamu Anemia” yang dilakukan pada bulan Maret-Desember 2018. Jumlah subjek sebanyak 83 orang dengan rentang usia 16-49 tahun. Data konsumsi makanan dikumpulkan dengan wawancara menggunakan food recall 24 jam dan selanjutnya dianalisis dengan program Nutrisurvey. Hasil. Hasil penelitian menunjukkan bahwa sebagian besar subjek memiliki status gizi normal. Tingkat konsumsi zat besi, asam folat, dan seng subjek kurang dari AKG, konsumsi energi dalam kategori cukup, dan konsumsi protein, vitamin A serta vitamin C lebih dari AKG. Hasil uji bivariat chi-square menunjukkan tidak ada korelasi yang bermakna antara status anemia dengan konsumsi zat gizi (p>0,05). Kesimpulan. Wanita usia subur (WUS) yang menderita anemia rata-rata memiliki tingkat konsumsi zat besi, asam folat, dan seng kurang dari AKG

Borneo is known as the third largest island in the world, which has enormous biodiversity. For generations, the locals used to utilize surrounding plants to treat diseases and maintain their health. Hemorrhoid is one of the diseases which is often treated using medicinal plants. An ethnopharmacological study (RISTOJA) was conducted to find potential plants to be developed in Borneo island by interviewing selected local traditional healers. Identification of medicinal plants was performed, followed by descriptive and literature studies. The most important medicinal plants were defined using the calculation of frequency of citation (FC), use value (UV), and choice value (CV). In order to establish scientific evidence, a literature review was conducted focused on the benefit and toxicity using electronic search engines Pubmed, DOAJ, Scopus, and Google Scholar. The evidence was collected from empirical use to in-vitro, animal, or clinical studies. There were 49 species under 31 families used in herbal formula for hemorrhoids. Based on FC, UV, CV, and literature review, Curcuma longa L., Graptophyllum pictum (L.) Griff., Melastoma malabathricum L., and Cocos nucifera were confirmed to have enough scientific evidence regarding its safety and efficacy. Accordingly, those plants have the potential to be further developed.

Abstract Physical fitness is a person’s ability to complete daily tasks without experiencing significant fatigue. Components of physical fitness consist of body composition, muscle flexibility, muscle strength, and cardiovascular fitness. Pre-clinical trials of herbal formula temulawak (Curcuma xanthorrhiza Roxb.), tumeric (Curcuma longa L.), and meniran (Phyllanthus niruri L.) can improve the fitness of test animals. The purpose of this study was to assess the safety and efficacy of temulawak, kunyit, and meniran herbal formulas for physical fitness. The research method in the form of quasi experimental pre and post with a placebo comparison involving 201 subjects divided into 2 groups. A total of 100 subjects in group I were given herbal medicine while group II as many as 101 subjects were given placebo for 6 weeks. The evaluation is based on the parameters of liver function, kidney, blood profile, and fitness component. The results showed that there were no significant changes (p≥0.05) in liver function, kidney function, blood profile, body composition, muscle flexibility, and muscle strength. Cardiovascular fitness in group I increased significantly (p<0.05) compared to group II. Temulawak, kunyit, and meniran formulas are safe for liver, kidney, blood profiles and can help improve physical fitness, especially cardiovascular fitness. Abstrak Kebugaran jasmani merupakan kemampuan seseorang menyelesaikan tugas sehari-hari tanpa mengalami kelelahan yang berarti. Komponen kebugaran jasmani terdiri dari komposisi tubuh, kelenturan otot, kekuatan otot, dan kebugaran kardiovaskular. Uji praklinis formula jamu temulawak (Curcuma xanthorrhiza Roxb.), kunyit (Curcuma longa L.), dan meniran (Phyllanthus niruri L.) dapat meningkatkan kebugaran hewan uji. Tujuan penelitian ini adalah menilai keamanan dan khasiat formula jamu temulawak, kunyit, dan meniran terhadap kebugaran jasmani. Metode penelitian berupa quasi experimental pre and post dengan pembanding plasebo yang melibatkan 201 subjek yang dibagi menjadi dua kelompok. Sebanyak 100 subjek kelompok I diberikan jamu sedangkan kelompok II sebanyak 101 subjek diberikan plasebo selama enam minggu. Evaluasi didasarkan atas parameter fungsi hati, ginjal, profil darah, dan komponen kebugaran. Hasil menunjukkan bahwa tidak terjadi perubahan bermakna (p≥0,05) pada fungsi hati, fungsi ginjal, profil darah, komposisi tubuh, kelenturan otot, dan kekuatan otot. Kebugaran kardiovaskular pada kelompok I mengalami peningkatan bermakna (p<0,05) dibanding kelompok II. Formula jamu temulawak, kunyit, dan meniran aman terhadap profil darah, hati dan ginjal serta dapat membantu meningkatkan kebugaran jasmani yaitu kebugaran kardiovaskular.

No abstract

Indonesians have had a close relationship with traditional herbal medicine for ages to maintain their health. As a common disease in the community, low back pain (LBP) is always considered for traditional healers in their practice. However, there are still insufficient data regarding the use of medicinal plants for LBP treatment. An ethnopharmacological study was conducted in Sumatra, Indonesia, to gain information on the empirical use of medicinal plants for LBP therapy among traditional healers. The information on the use of medicinal plants was gathered using semistructured questionnaires and interviews with traditional healers. The collected data were analyzed using several parameters such as family use value (FUV), use value (UV), and plant part used. A total of 90 traditional healers in Sumatra cited 68 plant species in 32 families that are used in their herbal formula for LBP treatment. They prefer to use leaves, roots, and barks than other parts of a plant. The calculation result of UV reveals that Kaempferia galanga is the most common plant used for LBP (0.04). Zingiberaceae was categorized as having the highest FUV. Datura metel was a toxic plant. The phytochemical and pharmacological screening of the indicated therapeutic plants should be investigated.

Hiperurisemia merupakan suatu keadaan dimana terjadi peningkatan kadar asam urat darah melebihi nilai normal. Cabe jawa (Piper retrofractum), daun sendok (Plantago major), dan seledri (Avium graveolens) diketahui memiliki khasiat sebagai penurun asam urat darah. Penggunaan kombinasi ketiga tanaman obat tersebut sebagai anti hiperurisemia belum pernah dilakukan sebelumnya. Penelitian ini bertujuan untuk menentukan khasiat ketiga tanaman tersebut dalam satu ramuan jamu. Jenis penelitian ini adalah eksperimental murni dengan pre and post test controlled design. Hasil intervensi selama 7 hari pada 30 ekor tikus putih jantan yang terbagi dalam 5 kelompok yakni kelompok kontrol (tanpa perlakuan), kelompok kontrol positif (allopurinol), kelompok ramuan jamu dengan 3 macam dosis masing-masing 0,2 g, 0,4 g dan 0,8 g, menunjukan bahwa kadar asam urat darah pada kelompok perlakuan mengalami penurunan. Pemberian ramuan jamu anti hiperurisemia dengan dosis 0,4 g mampu menurunkan kadar asam urat darah dengan rerata paling tinggi. Ramuan jamu  yang terdiri dari cabe jawa, daun sendok dan seledri mampu menurunkan kadar asam urat darah pada tikus.   Kata kunci: Cabe jawa, daun sendok, seledri, hiperurisemia

Barrang Lompo Island Waters is home for different species of marine biota of sea cucumber (Muelleria lecanora). Many sea cucumber species have been used as health supplements because they contain bioactive compounds that are beneficial to people in Indonesia. Given this, our study was designed to investigate the phytochemical, and antibacterial properties of crude acetone, methanol and hexane extract of sea cucumber using maceration extraction methods. The sea cucumber extract was prepared and the phytochemical profile was studied by analysing Gas Chromatography-Mass Spectrometry (GC-MS). Results showed that the extracts were a complex mixture of numerous compounds; many of which were present in trace amounts antioxidants and antimicrobial; hexadecanoic acid, methyl ester, 9-octadecenoic acid (z) -, methyl ester (stearic acid methyl ester), octadecanoic acid, methyl ester, 2-[(hexadecyloxy)methyl]oxirane, cholest5-en-3-yl acetate, ergosta-14,22-dien-3-ol, acetate,(3.beta.,5.alpha.,22e), 5,8,11,14- eicosatetraenoic acid, methyl ester, (all-z) epa/omega 3, pentacosane, hexatriacontane, and 9-hexadecenoic acid, methyl ester, (Z). The extract was also evaluated for activity against three pathogenic bacterial strains (Escherichia coli, Staphylococcus aureus and Salmonella) using the disc diffusion method. The extract exhibited clear zones of inhibition against the tested bacteria. Maximum inhibitory zone concentration values were demonstrated to be: Escherichia coli = 6.84 mm , Staphylococcus aureus = 7.22 mm, and Salmonella = 7.87 mm. These results revealed the significant potential of sea cucumber as a source of antioxidants and antimicrobial agents and also highlight the necessity of further purification and characterisation of solitary bioactive compounds for their prospective applications in pharmaceutical industries, food, and nutraceutical (food functional)

Alang-alang or Imperata grass known by people the Indonesian has many health benefits . RRJ Hortus Medicus as a service-based research clinic uses alang-alang roots in hebal formula to treat hypertension, osteoarthritis, headache, urinary tract stones, urinary tract infection,  stomatitis and prostate enlargement. In addition to having empirical usage data, all plants used in RRJ must have scientific data. This study is a literature study with the aimof obtaining the scientific basis for the use of alang-alang roots. Search articles from scientific journals through google scholar, google and pubmed search engines with the keywords alang-alang or Imperata cylindrica and assistive words in accordance with the claims of use. The selected article is a  complete of the results of experiments and surveys that are in accordance with topics both in Indonesian and English until 2018. The results of the study show that Imperata roots contain phenols and tannins which are antioxidants, isogeunin compound as anti-inflammatory, lignans as vasodilation, sinensitin, eupatorin, tetra-O-methylscutellar-ein 3 '-hydroxy-5,6,7 , 4 '-tetramethoxyflavone  as a diuretic, imperanene as platelet antiaggregation and 5-hydroxy-2- (2-phenylethyl) chromone and 5-hydroxy-2- [2- (2- hydroxyphenyl) ethyl chromone as neuroprotective . Imperata is also shown to have antimicrobial and anti-neoplasmic activity. The various active compounds and activities above, support the use of Imperata in the Hortus Medicus RRJ. Abstrak Tanaman alang-alang sejak dulu telah dikenal oleh masyarakat Indonesia memiliki banyak manfaat bagi kesehatan. Rumah Riset Jamu (RRJ) Hortus Medicus sebagai klinik penelitian berbasis pelayanan menggunakan akar alang-alang dalam ramuan jamu untuk mengobati hipertensi, osteoartritis, nyeri kepala, batu saluran kemih, infeksi saluran kemih, panas dalam, dan pembesaran prostat. Di samping memiliki data penggunaan empiris, semua tanaman yang digunakan di RRJ harus memiliki data ilmiah. Kajian ini merupakan studi literatur dengan tujuan memperoleh  dasar ilmiah penggunaan akar alang-alang di RRJ. Penelusuran artikel dari jurnal ilmiah melalui mesin pencari google scholar, google, dan pubmed dengan kata kunci alang-alang atau Imperata cylindrica dan kata bantu sesuai dengan klaim penggunaannya. Artikel yang dipilih adalah artikel lengkap hasil eksperimen maupun survei yang sesuai dengan topik baik berbahasa Indonesia maupun Inggris sampai tahun 2018. Hasil studi menunjukkan akar alang-alang mengandung fenol dan tanin yang bersifat sebagai antioksidan; senyawa isogeunin sebagai anti inflamasi; lignan sebagai vasodilatasi, sinensitin, eupatorin, tetra-O-methylscutellar-ein 3’-hydroxy-5,6,7, 4‘-tetramethoxyflavone sebagai diuretik; imperanene sebagai antiagregasi trombosit dan serta 5-hydroxy-2-(2-phenylethyl) chromone dan 5-hydroxy-2-[2-(2- hydroxyphenyl) ethyl chromone sebagai neuroprotektif. Alang-alang juga terbukti memiliki aktivitas antimikroba dan anti neoplasma. Berbagai kandungan senyawa aktif dan aktivitas di atas, mendukung penggunaan alang-alang di RRJ Hortus Medicus.