In the title compound, C19H16O3, the dihedral angle between the chromanone moiety and the methoxy phenyl ring is 16.47 (1)°. In the crystal, the molecules are linked by pairs of C—H...O hydrogen bonds, generating R
2
2(14) inversion dimers; further C—H...O hydrogen bonds connect the dimers into [100] double chains.
In the title naphthalene derivative, the mean plane of the naphthalene ring system makes dihedral angles of 65.24 (12)° with the dimethylphenyl ring and 55.82 (12)° with methoxyphenyl ring. The latter two rings are inclined to each other by 59.28 (14)°.
In the title compound, C41H41N3O9·2.25H2O, the cyclohexanol ring adopts a chair conformation. The cyclohexanol ring makes dihedral angles of 87.89 (7) and 75.53 (8)° with the mean planes of the trimethoxyphenyl rings and dihedral angles of 84.18 (8), 85.07 (7) and 82.03 (8)° with the pyridine rings. In the crystal, the packing is stabilized by C—H...O, O—H...O and O—H...N hydrogen bonds involving water molecules and methoxy O atoms, resulting in a supramolecular network. One of the methoxy groups is disordered over two sets of sites with occupancy factors of 0.63 (3) and 0.37 (3).
In the title molecule, C 13 H 17 NO 2 , the piperidine ring assumes a chair conformation. The dihedral angle between the mean plane of the piperidine ring and the benzene ring is 45.49 (1) . In the crystal, molecules are linked by O-HÁ Á ÁO intermolecular hydrogen bonds, leading to a molecular chain running along the c-axis direction. The atoms of the hydroxy piperidine ring and the methyl group of methylphenyl ring are disordered over two sets of sites with refined occupancies of 0.754 (5) and 0.246 (5).
Structure descriptionPiperidine and its derivative have played vital roles in the design of pharmaceutical drugs (Das & Brahmachari, 2013). It has been shown that the antioxidant activity of the title molecule can be enhanced by the substitution of hydroxyl, methoxy, nitro and alkyl groups on the piperidine ring system (Ravindernath & Reddy, 2017).In the compound (Fig. 1)
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