Introduction: Current studies suggest that tears and conjunctival secretions may be an important transmission route in coronavirus disease 2019 (COVID-19). The study aims to evaluate the presence of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) virus in tears and conjunctival secretion of patients with COVID-19. Methodology: A prospective interventional case series study was performed, and 32 patients with COVID-19 were selected at the Pamukkale University Hospital from 15 to 22 May 2020. The tear and conjunctival samples were collected by a conjunctival swab. Each specimen was sent to the laboratory for reverse transcription-polymerase chain reaction (RT-PCR) analyses. To avoid cross-infection, gloves and personal protective equipment were changed after collecting each sample. Results: 32 patients (18 male, 14 female) with Covid-19 were included in this cross-sectional study. The average age of the patients was 52.81 ± 16.76 years. By the time of the first collection of conjunctival-tear samples, the mean time of the onset of complaints was 6.84 ± 6.81 (1-35) days. Tear-conjunctival samples from 5 patients (16%) without conjunctivitis yielded positive PCR results, 3 of whom had positive and 2 negative nasopharyngeal PCR results. Conclusions: Five of 32 patients (16 %) without conjunctivitis or any eye symptoms had viral RNA in their tear-conjunctival samples. The possibility of transmission via tears and conjunctival secretions should be recognized even in the absence of conjunctivitis or other ocular manifestations.

Objectives Coronavirus disease 2019 (COVID-19) is a kind of viral pneumonia which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MicroRNAs (miRNA) are small non-coding RNAs consisting of 19–25 nucleotides and play a role in post-transcriptional gene regulation. We have focused on serum expression levels of microRNA (miRNA) a novel concept of in host–virus interactions. MicroRNA expression profiles were investigated in serum samples of COVID-19 patients. Materials and methods The samples were collected from 40 patients diagnosed with COVID-19 patients and from 10 healthy controls. Expression profile of 20 miRNAs were examined using a quantitative real-time polymerase chain reaction (qPCR). Results Statistically significant expression level differences (p < 0.05) were detected in nine miRNAs in COVID-19 patients and healthy controls. 7 miRNAs (hsa-let-7d, hsa-miR-17, hsa-miR-34b, hsa-miR-93, hsa-miR-200b, hsa-miR-200c, hsa-miR-223) expression levels were found to be significantly decreased and the expression levels of 2 miRNAs (hsa-miR-190a and hsa-miR-203) significantly increased respect to healthy controls. Conclusions We expect that a miRNA profile can be beneficial for the diagnosis of the COVID-19. Our result revealed that the increase in hsa-miR-190a level may be a prognostic factor related to the COVID-19 disease.

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ÖZETBu araştırmanın amacı, üniversite öğrencilerinde yaşam doyumu ve öz-duyarlık arasındaki ilişkiyi ortaya koymak ve öz-duyarlık düzeyinin cinsiyet açısından farklılaşıp farklılaşmadığını incelemektir. Araştırma bir devlet üniversitesinde okuyan 1082 öğrenci ile gerçekleştirilmiştir. Araştırma verilerinin toplanmasında Öz-Duyarlık Ölçeği, Yaşam Doyumu Ölçeği ve Kişisel Bilgi Formu kullanılmıştır. Verilerin analizinde Korelasyon analizi ve Çok Yönlü Varyans Analizi teknikleri kullanılmıştır. Araştırma sonucunda yaşam doyumu; öz-duyarlığın olumlu alt boyutları olan öz sevecenlik, bilinçlilik ve paylaşımların farkında olma ile pozitif, öz-duyarlığın olumsuz alt boyutları olan öz yargılama, izolasyon ve aşırı özdeşleşme ile negatif ilişkili çıkmıştır. Öz-duyarlık ölçeğinin bilinçlilik boyutunda erkekler kadınlara göre daha yüksek puan ortalaması almışlardır. Aşırı özdeşleşme boyutunda ise kadın öğrenciler, erkek öğrencilere göre daha yüksek puan ortalaması almışlardır. Bulgular ilgili alan yazını ışığında tartışılmış, gelecek araştırmalara yönelik öneriler sunulmuştur. Anahtar Kelimeler: Öz duyarlılık, yaşam doyumu, üniversite öğrencileri SELF COMPASSION AND LIFE SATISFACTION AMONG UNIVERSITY STUDENTS ABSTRACTThe purpose of this study was to examine relationship between life satisfaction level and selfcompassion level of university students, and whether self-compassion level differs according to gender. The study is conducted with 1082 students from 1.th, 2.th, 3.th and 4.th grades. SelfCompassion Scale, Life Satisfaction Scale and Demographic Form were used to collect data. Correlation analysis and MANOVA were used to analyze the data. The results indicate that life satisfaction had positive and significant correlations with subscales of Self-compassion Scale; self-kindness, mindfulness and common humanity and had negative correlations with negative subscales of Self compassion Scale; self-judgment, isolation and over identification. Females had significantly lower scores than males on the mindfulness subscale and females had significantly higher scores than males on over identification subscale. The results of study were discussed according to relevant literature and recommendations for the future studies were made. Key Words: Self-compassion, life satisfaction, university students, gender Bu amaçla araştırmada aşağıdaki sorulara yanıt aranmıştır.1-Üniversite öğrencilerinin yaşam doyum ve öz-duyarlık düzeyleri nedir? 2-Üniversite öğrencilerinin öz-duyarlık düzeyinin alt faktörleri ile yaşam doyum düzeyleri arasında anlamlı ilişkiler var mıdır? 3-Üniversite öğrencilerinin öz-duyarlık düzeylerinin alt faktörleri cinsiyete göre anlamlı farklılık göstermekte midir? YÖNTEM Araştırma ModeliAraştırma betimsel bir çalışmadır. Araştırmada üniversite öğrencilerinin öz-duyarlık düzeyleri ve yaşam doyumları arasındaki ilişkinin incelenmesi amacıyla ilişkisel tarama modeli kullanılmıştır. Araştırmanın diğer bir değişkeni olan öz-duyarlık düzeyine ilişkin bulgulara göre, Öz duyarlık toplam puanın yorumlanması, 1-2.5 arası puan...

Neutropenic enterocolitis is also known as typhlitis, is characterized by severe inflammation in the bowel loops. It is often seen in immunosuppressed patients, and it has high morbidity and mortality. Although the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the respiratory system and causes COVID-19 (Coronavirus Disease 2019), it may affect hematopoietic and gastrointestinal systems. Herein, we present a rare case of COVID-19-associated pancytopenia and typhlitis in a 60-year-old female who presented with abdominal pain. Contrast-enhanced abdominal computed tomography (CT) demonstrated the bowel wall thickening in the cecum and ascending colon compatible with enterocolitis. Moreover, the chest CT showed bilateral, peripheral, and multifocal ground-glass opacities, consistent with COVID-19 pneumonia. We also aimed to emphasize the laboratory, clinical, and CT findings of the patient.