Reflectance confocal microscopy is a reliable diagnostic technique for evaluation of skin photoaging with objective criteria. With the new emerging compact models it is possible to scan even the least accessible body parts with no discomfort to the patient, which offers the possibility to assess the effect of antiaging applications and to identify early signs of solar damage in cosmetically sensitive areas.

Demodex mite density was markedly increased in both ETR and PPR patients. It is believed that the presence of demodex mites plays an important role in rosacea aetiopathogenesis. Demodex mite treatment may reduce the severity of the disease and slow its progressive nature.

Reflectance confocal microscopy is a fast, direct and noninvasive method for Demodex-associated diseases and it is superior to SSSB for Demodex mite detection.

Most authors believe that vestibular papillomatosis (VP) is an anatomical variant of the vestibular mucosa. But VP is sometimes misdiagnosed as genital warts and this can lead to aggressive investigations, therapy, and anxiety in patients. We present a patient with VP. Dermoscopy and reflectance confocal microscopy (RCM) were performed to differentiate VP from other papilomatous diseases of the vulva.

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Lösemi, nonspesifik reaktif deri lezyonlarına veya neoplastik lenfositlerin deriyi infiltre etmesine bağlı olarak "lösemi kutis" olarak adlandırılan lezyonlara sebep olabilir. Çok sayıda lösemi türü, deri infiltrasyonu yapabilir. Çocuklarda daha sık olarak akut lenfoblastik lösemi (ALL) ile ilişkili olmakla birlikte, erişkinlerde daha sık olarak akut miyeloid lösemi (AML) hastalarında görülür (1). Lösemi kutis, en sık olarak eritemli papül, nodül ve plaklar şeklinde ortaya çıkar; genellikle bu hastalarda, trombositopeni de eşlik ettiği için lezyon hemorojik karakterde olabilir. Burada, AML tanısıyla takip edilen ve farklı karakterlerde lezyonlarla seyreden lösemi kutis olgusu sunulmaktadır. Olgu Sunumu Yetmiş beş yaşında kadın hasta, sol el sırtında ve sol kolda 1 haftadır devam eden, pembemor renkli kabarıklık şikayeti ile başvurdu. Hastaya yaklaşık iki ay önce halsizlik şikayeti ile başvurduğu hematoloji bölümü tarafından AML (French-American-British sınıflaması: M0-M1) tanısı konarak, 1000 mg/ gün hidroksiüre ve 300 mg/gün allopurinol başlanmıştı. Dermatolojik muayenesinde, sol ön kol, ekstansör yüz üst 1/3'te, üç cm çaplı, periferinde pembe renkli sınırları keskin olmayan eritemin izlendiği, ortası parlak mor renkli, orta derecede infiltre ve sol el sırtında çapları 10 mm ve 15 mm olan, iki adet pembe eritemli, hafif infiltre, asemptomatik plaklar tespit edildi (Resim 1a, b). Fizik muayenesinde, deri ve mukozalar

Multinucleate cell angiohistiocytoma (MCAH) is a benign fibrohistiocytic and vascular proliferation that it is seen on the dorsae of the hands or lower extremities in elderly women. Six cases, three males and three females, who had multiple or solitary asymptomatic skin lesions were admitted to our clinic. Histopathological examinations revealed vascular proliferation, perivascular lymphoplasmacytic, fibrohistiocytic infiltration and multinucleated stromal cells in the dermis. Based on the clinical and pathological findings, the diagnosis was MCAH. MCAH shows a slow but progressive course. MCAH is an entity that is not requiring any treatment. However, it is not well known by clinicians or pathologists and misdiagnosis may lead to unnecessary investigations and therapy. It should certainly be taken into consideration during differential diagnosis of cutaneous vascular proliferations.