A high prevalence of parasitic infections among children in the region was found, including a relatively high prevalence of Fasciola spp. infection. Epidemiological studies on the magnitude of parasitic infections in different regions will enable high-risk communities to be identified and allow for planning of appropriate interventions.

BackgroundSheep pox and goat pox are contagious viral diseases of sheep and goats, respectively. The diseases result in substantial economic losses due to decreased milk and meat production, damage to hides and wool, and possible trade restriction. A study was undertaken in Amhara region of Ethiopia. A cross-sectional study design was used to estimate the sero-prevalence and identify associated risk factors, while retrospective study design was used to assess the temporal and spatial distribution of the disease. A total of 672 serum samples were collected from 30 Kebeles and tested using virus neutralization test.ResultsFrom a total of 672 sera tested, 104 (15.5%) were positive for sheep and goat pox virus antibody; from which 56 (17%) were sheep and 48 (14%) were goats. The diseases were prevalent in all study zones, the highest sero-prevalence was observed in South Gondar (20.9%) and the lowest in North Gondar and West Gojjam zones (11.9% each). From the potential risk factors considered (species, sex, age, agro-ecology and location); only sex and age were significantly associated (p < 0.05) with the diseases in multivariable logistic regression. Female and young animals were at higher risk than their counterparts. From January 2010 to December 2014, a total of 366 outbreaks, 12,822 cases and 1480 deaths due to SP and 182 outbreaks, 10,066 cases and 997 deaths due to GP were recorded in Amhara National Regional State.ConclusionBoth the serological and the outbreak data revealed that sheep and goat pox is one of the most prevalent and widespread diseases of sheep and goats in the study area. Hence, annual mass vaccination program must be implemented for economic and viable control of sheep and goat pox diseases in the Amhara region in particular and at a national level in general.Electronic supplementary materialThe online version of this article (10.1186/s12917-017-1312-0) contains supplementary material, which is available to authorized users.

A cross-sectional calf mortality study was conducted in urban and periurban dairy farms in Addis Ababa, special zones of Oromia and Amhara regions in July and August 2015. e objectives of the study were to estimate the annual mortality and to assess the major causes of calf mortality in the dairy farms. One-year retrospective data on calf mortality were collected from 330 farms by face-to-face interview using the pretested and structured questionnaire format and direct observation of farm practices. A logistic regression analysis was performed in order to identify the predictor variables associated with early calf mortality. Data were analysed using Statistical Package, Stata SE for Windows, version 12.0. e annual mean calf mortality from birth-to-weaning was reported as 18.5% (95% CI: 12.6, 24.3%). e prenatal loss due to fetal death and stillbirth was 10.1% (95% CI: 6.7, 13.6%). e overall annual loss due to fetal death and calf preweaning mortality was 26.7% (95% CI: 21.2, 32.2%). Age-specific mortality declined with increased age, and the highest mortality was recorded during the first month of life extending up to the third month of age. Disease was the most important causes of calf mortality (73.2%). Among the diseases, diarrhea (63%) and respiratory disorders (17%) were the important causes of calf mortality. Malpractices in calf management were identified, including restricted colostrum and milk feeding, poor care and supplemental feeding, and poor health management. Interventions in dairy cattle health and farm husbandry are recommended to control calf mortality.

An experimental study was conducted to evaluate the effect of vaccines produced in Ethiopia from vaccine strains used worldwide on the transmission characteristics of velogenic Newcastle disease virus field strain after different vaccination schemes. Chickens were vaccinated with Hitchner B1, La Sota or I-2 via the intraocular and intranasal routes. Vaccine and challenge viruses induced high antibody levels, both in inoculated and contact birds. Prime-boost vaccination protected birds against morbidity and mortality and significantly reduced the incidence of viral shedding from chickens compared with single vaccinated and unvaccinated birds. Protection from disease and mortality was correlated with the presence of positive antibody titres (>4 log2) at day of challenge. Most of the unvaccinated and in-contact birds excreted the virus and showed a high level of antibody titres, indicating the high infectivity of the challenge virus. The detection of the challenge virus in most of vaccinated birds demonstrated that the tested vaccination protocols cannot fully protect birds from viral infection, replication and shedding, and vaccinated-infected birds can act as a source of infection for susceptible flocks. The high mortality observed in unvaccinated birds and their contacts confirmed the virulence of the challenge virus and indicated that this field virus strain can easily spread in an unvaccinated poultry population and cause major outbreaks. Progressive vaccinations supported by biosecurity measures should therefore be implemented to control the disease and introduction of the virus to the poultry farms.

Trachoma is a classical disease of poverty. It is still the second leading cause of blindness in Ethiopia. Cognizant of the poor living condition of its people, every effort of the current government of Ethiopia is geared towards eradication of extreme poverty. The main aim of this study was to assess the current status and correlates of active trachoma among elementary school students. A cross sectional school-based study was conducted in Dangla town administration in the month of March 2012. Multistage sampling technique was employed. Pre-tested structured questionnaire and eye examination were data collection tools. The data were collected by health professionals especially trained for eye care. The data were analyzed using SPSS version 16 for windows. Possible associations, and statistical significance between, and among variables were measured using odds ratio at 95% confidence interval. The study indicated that overall prevalence of active trachoma was 12%. The multivariate analysis revealed that those children with unclean face were seven times more likely to develop active trachoma than those with clean face (AOR = 7.07, 95% CI: 3.36-14.96). Moreover, children who didn't use soap to wash their face were two times more likely to develop active trachoma than those who claimed to use soap to wash their face (AOR = 2.03, 95% CI 1.72-3.01). In short, the prevalence of trachoma is lower than the figures in previous survey reports in the region and at national levels; however, the risk factors remain the same. The struggle to eradicate extreme poverty should continue in a sustainable manner so that diseases of poverty including trachoma could be eliminated altogether.