Sustainable development of drug delivery materials with good biocompatibility and controlled-release is a popular topic among researchers. In this research study, we demonstrated the potential of the metal-organic framework, that is MIL-100(Fe), as a drug delivery platform for isoniazid (INH). The MIL-100(Fe) was prepared by using the hydrofluoric acid-free hydrothermal method. Several physical measurements were conducted to characterize the MIL-100(Fe), including x-ray diffraction (XRD), scanning electron microscopy (SEM), nitrogen sorption, and thermal-gravimetric (TG). The synthesized MIL-100(Fe) has octahedron-shaped particles with superior properties, that is large surface area (1456.10 m2/g) and pore volume (1.25 cm3/g). The drug loading rate and capacity were determined by means of adsorption kinetic and isotherm. The studied INH@MIL-100(Fe) adsorption system kinetics follow the pseudo-first-order model, while the isotherm system follows the Langmuir model with the maximum adsorption capacity of 128.5 mg/g at 30 °C. MIL-100(Fe) shows adequate biocompatibility, also exhibits a reasonable and controlled drug release kinetics. The results obtained show that MIL-100 (Fe) can be a good choice of drug delivery platform among other available platforms.
Coir fibres, a byproduct of the coconut industry, have high performance qualities but are difficult to process by conventional textile methods. The purpose of the research is to combine the processibility of hemp and flax with the high-performance properties of coir to create a composite product worthy of industrial applications. The evaluation of coir fibre-reinforced composites focuses on the processibility of the coir fibre into a nonwoven, how well it interfaces with polylactic acid and an analysis of how the mechanical properties of the final product change when mixing coir with hemp and flax. The results show that the hybrid samples outperformed most of the researched values for coir composites, despite the reduced properties of control samples as in comparable research. Adding just 10% of either flax or hemp dramatically increased the mechanical properties compared to the pure coir–polylactic acid composite.
This study examines sustainable agricultural development in the Mekong Delta, Vietnam by focusing on technology improvement for minimizing the environmental load in rice production with sufficient yield and quality. Among rice-producing countries, Vietnam is the third-largest rice export country worldwide. High-yield rice production is still a critical issue in Vietnam. However, in recent years, quality improvement and low environmental load agriculture have been fundamental issues. In this research, we conducted rice cultivation experiments in 2014, 2015, and 2017 under different conditions of planting density, fertilizer volume, rice variety, use of fertilizer applicator mounted on a transplanter, and use of high-density seedling mat called “Mitsunae.” We conducted 7 seasons with 79 planting patterns in experiments to compare yield, quality, and fertilizer volume in rice production. As a result of productivity achievement, high-density transplanting does not always produce a high yield. Each performance depends on transplanting density, rice variety, fertilizer volume, or other factors. In general, transplanting machine with a planting width of 25cm achieved a significant yield with short growing duration rice varieties. Those varieties are popular in the Mekong Delta. We conducted experiments of “high-density seedling mat” called “Mitsunae”, a new nursery technology developed in Japan, to reduce the environmental load and operating costs in rice production. With the “Mitsunae” method, we can reduce the number of rice seedling trays up to three times that of conventional seedling mats. Then, we can minimize the nursery surface area, nursery materials, and total working time, including transplanting time. The “life cycle assessment (LCA)” method is practical for correctly quantifying environmental load reduction. We investigated environmental load reduction caused by “Mitsunae” rice nursery process using LCA method in this research. We could achieve about 20% – 30% reduction of the “greenhouse gas (GHG)” emission volume and economic benefits created by the “Mitsunae” nursery process.
the demand for diesel fuel is 40% more than all the petroleum products, and the projected demand for petroleum products for 2025 is over 18 million tons (Table 1) 1) . On the other hand, Vietnam has a huge volume of agricultural and fisheries production output, creating an enormous amount of unused biomass resources that could be converted to biofuel. However, biofuel production in Vietnam is currently limited to bioethanol, mainly produced from cassava and BDF production is minimal.In our previous research for BDF popularization plan in Vietnam 2) , we surveyed and tested fundamental information and technology, such as 1) selection of original materials available in Vietnam for the production of BDF, 2) BDF Abstract: Diesel fuel usage in Vietnam is increasing rapidly, but most of it is imported from overseas. In this study, we investigated the possibility of popularizing bio-diesel fuel (BDF) made from Vietnamese origin resources as a sustainable energy solution. The world's energy cost fluctuates significantly depending on economic or political movements, especially after the Russian invasion of Ukraine began in 2022. This caused energy prices soar, attacking the global economy in a short period and requiring a wide range of energy supply sources. We aim to promote commercial BDF production in Vietnam for future energy security and contribution to the Vietnamese economy. Eight necessary factors were investigated to choose suitable material for BDF production. The factors are as follows: 1) material with Vietnamese origin, 2) sufficient and continuous supply volume, 3) sufficient quality to run diesel engines, including common-rail diesel engines, 4) inedibility, 5) low enough freezing point, 6) ease of collection, 7) affordability, and 8) availability of valuable elements in the material. If a suitable material candidate is not stable, it may be changed over time. In this study, the focus material was rubber seed oil. Because rubber production in Vietnam is quite stable with over 900,000 ha plantation area, and there is a potentiality to collect seeds and produce about 50,000 tons of BDF annually. In addition, the quality of rubber seeds based BDF is very high, such as low enough freezing point, etc. However, most of those rubber seeds are currently not collected and used.
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