BACKGROUND: Hypertension and hypercholesterolemia are most predisposition factors and show a significant impact in causing cardiovascular disease. Therefore, it is recommended to conduct dietary modifications, physical activity, and alternative therapies. One such option for alternative therapies is wet cupping therapy. AIM: This study aims to investigate the effect of wet cupping on blood pressure (BP) and total cholesterol (TC) on healthy young male adults. METHODS: This study design was quasi-experimental with a control and intervention group. It was conducted between January and February 2020 at Mini Hospital, School of Nursing, Universitas Muhammadiyah Yogyakarta. There were 44 healthy young male adults divided into control (n = 22) and intervention (n = 22) groups. This study’s outcomes were BP (systolic BP [SBP] and diastolic BP [DBP]) and TC. RESULTS: In the intervention group’s post-test, the mean SBP and DBP were substantially different from the pretest (p = 0.01 and 0.03). Although there was no statistically significant difference in TC outcome, overall cholesterol decreased following an intervention. There was no statistically significant difference in the outcome between the control and intervention groups, except for TC, which was significantly lower in the post-test than in the pre-test. CONCLUSION: This study’s results indicated that wet cupping could be useful in decreasing BP and total cholesterol.
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