A literature review on community studies of adolescent substance use, abuse, or dependence (SU/A/D) and psychiatric comorbidity yielded 22 articles from 15 studies with information on rates, specificity, timing, and differential patterns of comorbidity by gender, race/ethnicity, and other factors. Results revealed that 60% of youths with SU/A/D had a comorbid diagnosis, and conduct disorder (CD) and oppositional defiant disorder (not attention-deficit/hyperactivity disorder) were most commonly associated with SU/A/D, followed by depression. Child psychopathology (particularly CD) was associated with early onset of substance use and abuse in later adolescence. The authors suggest that available data relevant to SU/A/D and psychiatric comorbidity can be used to better address such questions.

The aim of the current article is to review the literature on religion and spirituality as it pertains to adolescent psychiatric symptoms. One hundred and fifteen articles were reviewed that examined relationships between religion/spirituality and adolescent substance use, delinquency, depression, suicidality, and anxiety. Ninety-two percent of articles reviewed found at least one significant (p < .05) relationship between religiousness and better mental health. Evidence for relationships between greater religiousness and less psychopathology was strongest in the area of teenage substance use. Methods of measuring religion/spirituality were highly heterogeneous. Further research on the relationship of religion/spirituality to delinquency, depression, suicidality, and anxiety is warranted. Measurement recommendations, research priorities, and clinical implications are discussed.

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The underrepresentation of African Americans in medical research is problematic for several reasons, including disparities in health outcomes, differences in metabolism of pharmacological agents, and accurate assessment of health needs and costs. This paper investigates factors contributing to African Americans' lower likelihood of consenting to participation in medical research. In Study 1, three focus groups were conducted to assess concerns about research participation and to generate further hypotheses for questionnaire development. Study 2 presented a hypothetical clinical trial and collected questionnaire data on attitudes about participation. Both studies revealed a greater likelihood to mistrust the medical establishment among African American students. However, suspicion did not contribute to a decreased likelihood of participation. Several recommendations are offered regarding the recruitment of African Americans in research.