Summary:The aim of this study was to observe membrane injury and to investigate the mechanism of antioxidant defence Systems against acute ethanol toxicity. Erythrocyte Superoxide dismutase and Na" 1 ", K^-ATPase activities were significantly decreased and catalase levels were significantly increased one hour after ethanol intoxication of male swiss albino rats. These data demonstrated that Superoxide dismutase and catalase are susceptible to lipid peroxidation and that these enzymes protect tissues from free radicals. The possible mechanism involved in Na + , K + -ATPase and Ca 2 " 1 "-ATPase Inhibition are discussed in relation to the development of ethanol toxicity and the role of lipid peroxidative processes.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.