The presence of pleural effusion predicts poor PFS and OS in lung adenocarcinoma patients receiving TKIs as the first-line treatment. Additional studies are warranted to elucidate the underlying mechanisms and determine novel strategies for improving the outcome of these patients.
Review question / Objective: Is mortality rate different in acutely ill patients with liberal oxygen therapy compared to conservative oxygen therapy? Condition being studied: The oxygen administration strategies in acutely ill adults are contradictory and inconsistent. Moreover, there is a lack of high-quality evidence and updated meta-analysis of the mortality in different way of oxygen administration in acutely ill adults. The main outcome of our study is the mortality INPLASY 1
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