The displayed medium sensitivity and specificity, and good positive predictive value of the LIPCOF test support the use of LIPCOF grading as a simple, quick and non-invasive dry eye screening tool.
In Hungary, the number of grafts has increased greatly in the past 64 years, the transplantation rates are similar to those of industrial countries. Indications for corneal transplantation have changed considerably over the last half decade from corneal scarring to corneal ectasia, regraft and pseudophakic/aphakic corneal oedema.
Acanthamoeba infection is a more and more frequently occurring disorder all over the world and in Hungary as well. Beside diagnostic and therapeutic possibilities it may cause serious visual loss. The characteristics of the disease are summarized and presented. It mainly affects people wearing contact lenses with poor hygiene. The subjective signs of the disorder are pain, red eye, tearing and eyelid swelling. In the clinical appearance the ring-shaped ulcer invading the corneal stroma is typical. From differential diagnostic point of view bacterial, fungal, and herpes simplex infection should be excluded. In the diagnosis confocal corneal microscopy and specific laboratory tests are recommended. A wide range of conservative and surgical treatment options are available for treatment. However, early diagnosis and long-lasting adequate therapy are necessary for effective recovery. Prevention is the most important task of contact lens specialists, to inform the patients about adequate hygiene and up-to-date contact lenses and cleaning solutions.
Early diagnosis and long-term suitable local therapy are necessary for effective recovery. If the patient wears contact lens and there is severe pain with ring infiltration in the cornea, Acanthamoeba infection should be considered and suitable therapy should be given. Immediately performed perforating keratoplasty does not lead to visual improvement. Prevention by informing the patients about adequate hygiene and use of the cleaning solutions is one of the most important tasks of contact lens specialists.
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