A large number of diseases may cause Atrophic skin disorders are caused by a large
number of diseases, some of them idiopathic and others inflammatory, in which there
is loss of volume of body segments. Localized scleroderma is a rare inflammatory
dermatosis, manifested by atrophic skin and subcutaneous tissue alterations.
Lipoatrophy may be genetically inherited or acquired as a result of panniculitis, HIV
infections or aging. Many treatments have been proposed. Results vary in the acute
inflammatory phase and are scarce when sclerosis and atrophy have already been
established. This article describes four cases of localized facial scleroderma and
one of facial idiopathic lipoatrophy treated with implantation of autologous fat
globules extracted from the infragluteal groove, without utilization of cannula
aspiration, with lasting results.
Acne fulminans is a rare manifestation that may occur during the evolution of acne vulgaris primarily in male adolescents. Use of isotretinoin, testosterone, and exacerbated immune responses in the body are related triggers. Signs, symptoms and laboratory findings such as fever, hepatomegaly, polyarthralgia, leukocytosis, plaquetose, increased inflammatory markers and transaminases, are characteristic. A bone scan can detect osteolytic lesions in multiple skeletal sites. The treatment is performed with prednisolone, isotretinoin and antibiotics if secondary infection is present. This case describes a male patient with a diagnosis of grade III acne, who developed acne fulminans and bilateral sacroiliitis with inability to ambulate, after initiation of therapy with isotretinoin.
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