We have demonstrated that NIPF does not correlate with the SNOT-22 disease-specific questionnaire, although both outcomes significantly improve postoperatively. At present, we are still lacking a clinically accurate objective measure of nasal function for the evaluation of patients undergoing septorhinoplasty surgery.

This study assesses quality of life in a group of self-selected patients who attended the patient-doctor thyroid cancer forum and, although accepting there is a sampling bias, the conference provided an opportunity to assess the quality of life of patients with differentiated thyroid cancer. The study has found that the average quality of life in this group of patients is lower than that of the UK population, and lower than that of patients with breast, colorectal and prostate cancer. A large number of these patients suffer with fatigue, and depression requiring anti-depressants and/or counselling.

To our best knowledge, this patient represents the first reported case of diffuse lipomatosis of the thyroid gland causing goitre in a patient with AA amyloidosis. The presence of amyloid protein within the thyroid was not sufficient to cause enlargement per se, and was therefore of unclear significance. Together with previous reports of the concurrent deposition of amyloid and fat, this case raises questions as to the relationship between these two phenomena.

ObjectivesNasal obstruction is a common presentation in ENT practice, and yet decisions on its management are challenging, with high rates of patient and clinician dissatisfaction following surgery. The aim of the study was to investigate the practice of UK ENT clinicians in the subjective and objective evaluation of nasal patency. DesignVoluntary, written questionnaire. SettingBritish Academic Conference in Otolaryngology 2015, Liverpool, UK. Participants UK-based ENT professionals. Results UK based rhinologists were surveyed at the 2015 British Academic Conference inOtorhinolaryngology (BACO) from a cohort of 250 delegates attending two symposia on rhinology with a response rate of 78/250. Clinical history and examination were found to be almost universally used in the evaluation of nasal blockage. The most commonly used clinical test was the nasal misting pattern demonstration on a metal spatula (73%), followed by the peak nasal inspiratory flow rate (19%). The most commonly used subjective measure was the sinonasal outcome test (SNOT-22/23), with a 29% uptake.63% of the responders reported that non-availability of suitable equipment was the main reason for not using objective measures, followed by time consumption, and the lack of correlation with subjective symptom scores. ConclusionsOur study demonstrated that British clinicians rely largely on clinical skills to evaluate nasal blockage. There is a desire for a simple, practical, non-invasive device which a) objectively measures airflow during physiological resting nasal breathing, b) correlates with subjective symptom scores, and c) is capable of simultaneous measurement of each nostril.

Background: Selected adult patients with obstructive sleep apnoea-hypopnea syndrome (OSAHS) may benefit from surgical intervention. At present, the dominant technique for the diagnosis of the anatomical locus of upper airway obstruction during sleep is drug-induced sedation endoscopy (DISE). This technique is widespread, but has generated controversy related to its artificiality. Methodology: We present a technique for the acquisition of high-quality and consistent recordings of snoring sounds, suitable for advanced acoustic analysis and correlation with the findings of DISE. Results: Analysis of the generated recordings demonstrates distinct frequency-domain characteristics of snoring sounds generated by distinct anatomical subsites, for example the soft palate, or tongue base. Conclusions: Supplemental information may potentially be obtained from the waveform of snoring sounds produced by the patient; however, no robust quantitative "assay" has been developed or been clinically validated. This may in part be related to inconsistencies or insufficient quality of the sound data acquired. This novel technique may circumvent these difficulties and permit more advanced analysis techniques with potential clinical applicability.