Chest pain: The importance of serial ECGsA 44-year-old man, previously well, presented to the emergency department with severe hypertension and a 4-hour history of typical angina-like chest pain with associated diaphoresis. He had dyslipidemia, a 5-pack-year history of smoking, and, likely, undiagnosed hypertension.On arrival, his blood pressure was 200/110 mm Hg, representing a hypertensive emergency. A clinical examination was unremarkable. A blood sample was sent for troponin analysis, and a nitroglycerin infusion was started.
Whilst we suspect that there is no clear association between the two major diagnoses we made in this patient during this hospitalisation (i.e. coronary artery disease and CMT neuropathy), the literature from a series of published case reports does perhaps show an association between CMT and abnormalities of cardiac conduction.
Percutaneous edge-to-edge mitral valve (MV) repair is a relatively new treatment option for mitral regurgitation (MR). After the feasibility and safety having been proved in low-surgical-risk patients, the use of this procedure has shifted more to the treatment of high-risk patients. With the absence of randomized controlled trials (RCT) for this particular subgroup, observational studies try to add evidence to the safety aspect of this procedure. These also provide short- and mid-term mortality figures. Several mortality predictors have been identified, which may help the optimal selection of patients who will benefit most from this technique. In this article we provide an overview of the literature about mortality and its predictors in patients treated with the percutaneous edge-to-edge device.
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