Objective: To describe the living conditions of Senegalese adolescent girls according to their migration status, and to define the main socio-economic and biological determinants of their nutritional and growth status. Design: Health and living conditions, sexual maturation, and nutritional and growth status of adolescent girls were determined within the framework of a longitudinal study on growth. Settings: The capital city of Senegal (Dakar) and a rural community (Niakhar), 120 km south-east of Dakar. Subjects: Three hundred and thirty-one girls, 14.5 -16.6 years of age, were recruited from the same villages. Thirty-six per cent of the sample remained in the villages to attend school and/or to help with household subsistence tasks (non-migrants). The remaining (64%) migrated to cities to work as maids (migrants) and lived in two different socio-economic environments: at the home of a guardian during the night and in the house of the employer during the daytime. Results: Family rural environment and guardian and employer urban environments were socio-economically different ðP , 0:001Þ: Living conditions in urban areas were better than in rural areas and the employer's environment was socio-economically more favourable. Migrants had more advanced sexual maturation and higher body mass index (BMI), fat mass index (FMI) and mid-upper arm circumference than nonmigrants. However, migrants were smaller than non-migrants. BMI, FMI and weightfor-age were related to socio-economic levels and duration of migration. Schooling was positively related to height and negatively related to BMI. Conclusions: Migrants enjoyed better living conditions than non-migrants. This could be partly due to the better socio-economic environment of the employer. It was associated with earlier puberty and better nutritional status, but not with a better growth.

Citation: IFSCC Magazine, 11 (2008) (2) 105–112 Abstract:  A novel photoprotective ingredient with anti‐oxidant and electrophilic scavenging properties was designed. A structure–activity relationship study was conducted in order to optimize its bioavailability, specifically its ability to reach deep layers of the skin that may be affected by ultraviolet radiation‐induced oxidative stress. A particular characteristic of this compound is its ability to release taurine upon reaction with some reactive oxygen species. In situ taurine formation may contribute to photoprotection. Preliminary in vitro experiments provide some evidence for effective protection against UVA‐induced oxidative stress. Scavenging of the electrophilic species 4‐hydroxynonenal, a highly cytotoxic end product of membrane lipid peroxidation, seems to be 2‐oxo‐1,3‐thiazolidine major photoprotective mechanism. Keywords:  antioxidant, electrophilic species scavenging, photoprotection, structure‐activity relationship, taurine Paper presented at the IFSCC Conference 2007, Amsterdam, The Netherlands