The objective of the study was to identify and analyse the research done on the occurrence of cancer among pesticide applicators by conducting a systematic review of the scientific literature. PRISMA Guidelines was followed to conduct the study. Search was done in Scopus, PubMed, Embase, MEDLINE and Google Scholar databases with search terms “PESTICIDE APPLICATORS”, “CANCER” using Boolean operator “AND”. Meta-analysis and review articles were excluded from the study. A total of 32 studies were identified among which the average sample size was found to be 60,521. Increased RRs/ORs and positive exposure–response relationships were observed for 31 pesticides. Organophosphate and organochlorine classes of pesticides were the most to be associated with cancer. Lung cancer was observed the most followed by prostate, multiple myeloma and colon cancers among pesticide applicators. It was concluded that there is an increased risk of cancer among the pesticide applicators, whereby which bringing into focus the need to educate and train the workers on following adequate safety measures and making them aware of the hazardous chemicals. Further evaluation on the carcinogenicity of pesticides is also required.
Snakebite is an acute life-threatening and time-limited medical emergency. There is comparatively less evidence regarding the infections caused by pathogens present in the snake's oral flora that induce cellulites secondary to snake bite. Here, we report a case of 15-year-old male patient infected with Acinetobacter baumannii-induced sepsis who underwent hemodialysis posthemotoxic envenomation; inflicted by hemotoxic snake, Russell's viper (Daboia russelii) at right index finger, and he was treated with 20 vials of antisnake venom. He had acute kidney injury and underwent 10 cycles of hemodialysis. He had incidence of cellulites with sepsis, and pus culture showed the presence of A. baumannii isolates with extensive drug resistance. He was treated with piperacillin-tazobactam, vancomycin, imipenem, and colistin for the improvement of his health status. Thus, the management of snake bite-induced sepsis, bacterial susceptibility study of oral flora in local venomous snakes has to be studied.
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