The objective of the study was to identify and analyse the research done on the occurrence of cancer among pesticide applicators by conducting a systematic review of the scientific literature. PRISMA Guidelines was followed to conduct the study. Search was done in Scopus, PubMed, Embase, MEDLINE and Google Scholar databases with search terms “PESTICIDE APPLICATORS”, “CANCER” using Boolean operator “AND”. Meta-analysis and review articles were excluded from the study. A total of 32 studies were identified among which the average sample size was found to be 60,521. Increased RRs/ORs and positive exposure–response relationships were observed for 31 pesticides. Organophosphate and organochlorine classes of pesticides were the most to be associated with cancer. Lung cancer was observed the most followed by prostate, multiple myeloma and colon cancers among pesticide applicators. It was concluded that there is an increased risk of cancer among the pesticide applicators, whereby which bringing into focus the need to educate and train the workers on following adequate safety measures and making them aware of the hazardous chemicals. Further evaluation on the carcinogenicity of pesticides is also required.
Autosomal dominant polycystic kidney disease (ADPKD) is an inherited condition that causes small fluid-filled sacs called cysts to develop in the kidneys. ADPKD affects 1 in 500–1000 people. We report the case of a 70-year-old male patient with complaints of difficulty in passing urine, lower abdominal pain, fever with chills, and hematuria. The ultrasonography report of the abdomen and pelvis showed bilaterally mildly enlarged kidneys with multiple variable simple cysts slightly distorting the normal renal architecture and mildly increased residual visualized cortical echoes concerning adult polycystic kidney changes. The therapeutic regimen was targeted to treat the symptoms of the patient. In India, there is a need for epidemiological studies on ADPKD since insignificant data are present that could rationally reflect its prevalence and incidence, for which this case report could be utilized.
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