Arrhenius parameters have been determined for two nucleophilic reactions involving a series of alicyclic bromides and one secondary aliphatic bromide:
Irreversible SN2 halogen exchange: RBr + I−→ RI + Br− using potassium iodide in anhydrous acetone.
Solvolysis in 40,9% aqueous dioxane
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The extent of reaction was determined by conductivity measurements.
The relative reactivities observed for the medium and large ring compounds are discussed in terms of an internal steric effect and a transannular interaction effect.
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