No abstract

The postpartal thickness of the amniochorionic membrane was measured by means of 20 MHz ultrasound after 28 inconspicuous deliveries in the course of a prospective study. The aim of our investigation was to determine the thickness of the amniochorionic membrane using high frequency ultrasound and to evaluate the results for a statistical correlation with fetal and maternal parameters. The data obtained were compared with histological sections for measurement accuracy using a linear regression analysis method. Membrane thickness of the total study group was 0.83 +/- 0.11 mm (0.72-1.08 mm). Based on a statistical comparison with the histological sections, the high frequency ultrasonographic examination was shown to be highly reliable with a correlation coefficient of r = 0.96 (p < 0.0001). Results obtained by ultrasonography were correlated with maternal (gestational age, patient age, parity) and neonatal (size and weight at birth, sex, placental weight, Apgar 1/5/10) parameters by means of linear regression analysis. There was a statistically significant correlation between parity and membrane thickness (r = 0.485, p < 0.05). There was also a correlation of Apgar scores at 5 minutes post partum (r = 0.485, p < 0.05). We were able to demonstrate that the measurement of membrane thickness by ultrasound is an objective and reliable method and may be a gain to prenatal diagnostics when used in vivo.

Zusammenfassung: Bei 81 Schwa nge ren mit unauffällige r Anamnese (40 PrimiparaJ41 Multipa ra) wu rde unmittelbar post parturn. no ch vor l ösung der Plazenta, die rruct osa mtn-, 5TH ('" Somatotropes Horm on)-und Som atomed in c-konzentrattcn im Nabelschnurvenenb lut bestimmt. um eine mögliche Korrelat io n mit Geburtsgewicht-und-läng e zu untersuchen. Die Kor relation wurde mit Hilfe de r linea re n Regression üb erprüft. Die Konzentrationen im Nabe lschnurblut waren im Falle de s Fructosa min 170,4 ± 22,5 rncmclj l, bei 5TH 24,1 ± 18,1 ngfml sowie im Falle des Somatomedin-C 0,4 ± 0.12 U/ml. Eine sig nifikante Korrelati on kon nte zwischen dem Somatomedin (-Spiegel (= ICF I) un d Geb urts-und Plazentagewicht gefun den werden (p < 0,05). Es zeigte sich eine deutliche Abhängigkeit des 5TH-Spiegels vom kind liche n Geschlecht (39 we ibliche und 42 mä nnliche Kinde r) mit eine m p < 0,04 3 (St udent t-Test). Die Korrelat ion der We rte des Aminoz ucke rs Fructosamin sowie des Somatotropen Hormons mit der Geburtslänge und dem Geburtsgewicht wa r statistisc h nicht signifika nt. Som it könnte die Somatomedin (-Bestim mung eine n wese nt liche n Parame ter zur Erkennung feta ler bzw. frühkind liche r Wachst um sstö rungen da rst ellen. Fructosamine-. Growth Hormonea n d Somatomedin c-Levels In Umbilical Cord Blood in Correlation to Birth Weight: In 81 preg nancies (40 primiparaf41 multipara) with incons picuous history, post pa rtal veno us blood conce ntrat ions of fructosa mine, growth ho rmo ne , and so matome din-C in the umbilical cord we re measured to determine a possible correlation with th e birth weight and height (befo re delivery of t he placenta). This cor relat ion was sta t ist ically prov ed by linea r reqr ession. The ser um levels in the um bilical cord blood were in t he case of fruetosam ine 170.4 ± 22.5 mcmo lfl, STH 24,1 ± 18,1 ngl ml a nd somat omedin-C 0.4 ±0.1 2 Ufm l. A significant correlation was found fo r somatome din-((= IFG I) concentration and we ight of the newborn and weig ht of placenta (p <0.05). Furt her somatomedin C con ce ntrat ion de pends on the gender (39 fem ales, 42 males) with a significance of p < 0.043. The re was no significance between fruct osamine, STH-conce nt ration a nd birt h weig ht an d height. It seems t hat the eva luatio n of somato medin-C cou ld be a usef ul diag nost ic param eter for fetal and pae diat ric growth deficits .