We describe à case of acute disseminated encephalomyelitis occurring after COVID-19 pneumonia in a 25-year woman. She presented with confusional syndrome and heaviness on the left side. Magnetic Resonance Imaging with gadolinium showed asymmetrical and bilateral hyperintense lesions within the deep white matter. The patient’s clinical symptoms resolved after corticosteroid therapy. Acute disseminated encephalomyelitis should be considered in patients with COVID-19 who present with altered mentation and neurological deficits.
Spinal cord ischemia is exceptionally uncommon, accounting for 0.3–1% of all strokes. Here, we reported the case of a 64-year-old patient with spinal cord ischemia secondary to atrial fibrillation. Spinal magnetic resonance imaging showed increased intramedullary signal intensity at the T9 level in T2-weighted. An electrocardiogram showed atrial fibrillation. The patient was given corticosteroids and antiplatelet agent therapy. After 8 weeks of rehabilitation, the patient was able to walk with the support of a medical walker.
Malignant spinal cord compression is defined as an extra or intradural lesion of the spinal cord, most often caused by bone metastases, which is responsible for medullary suffering. Our work is a retrospective study, spread over four years (January 2017- December 2020), on 16 cases of neoplastic spinal cord compression, treated in Moulay Ismail military hospital of Meknes. The average age of the patients was 62.69 years. A clear male predominance was observed with 81.25% of men. Also, 81.3% of patients had documented neoplasia at the time of diagnosis of spinal cord compression. The clinical presentation at admission was paraplegia in 18.8% of patients, paraparesis in 43.8%, and tetraparesis in 6.3%. Rachialgia was present in 83.3% of cases. The lesions were cervical in 6.25% of patients. The etiologies of spinal cord compression in our series were dominated by bone metastases secondary to prostate cancer, found in 50% of our cases. All patients received corticosteroid therapy and radiotherapy. 18.75% of the patients underwent laminectomy with spinal stabilization. The evolution was marked by a complete or partial recovery in 62.5% of our patients.
Paraneoplastic neurologic syndromes are a group of rare disorders that are triggered by an abnormal immune system response to a neoplasm. In order to increase our knowledge about these rare syndromes, we present three cases with paraneoplastic neurologic syndrome after breast cancer, small cell lung cancer and esophagogastric junction adenocarcinoma.
Encephalopathy/encephalitis syndrome with reversible splenial lesion (MERS) is a clinical-radiological syndrome, combining encephalopathy and a specific radiological picture. MERS is caused by many factors, and the main pathogenesis is due to virus infection. Here, we reported the case of a 25-year-old patient with MERS following tuberculosis meningitis.
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