Tuberkulosis merupakan penyakit yang disebabkan oleh Mycobacterium tuberculosis yang menyerang organ paru. Adanya peradangan Tuberculosis didalam tubuh ditandai dengan respon inflamasi. Respon inflamasi didalam tubuh dapat didiagnosa melalui pemeriksaan C Reactive Protein sebagai respon anti infeksi imun didalam tubuh seseorang. Biasanya adanya peningkatan kadar C Reactive Protein mengindikasikan infeksi yang tidak terkontrol. Selain pemeriksaan tersebut, pemeriksaan penanda lainnya dapat dilihat dari pemeriksaan hematologi seperti hitung jenis neutrofil. Tujuan penelitian ini untuk mengetahui hubungan kadar C Reactive Protein dengan jumlah neutrofil pada penderita tuberkulosis paru dengan fase pengobatan 0 dan 6 bulan di BKPM Kabupaten Banyumas. Penelitian ini menggunakan metode observasional analitik dengan rancangan Cross-sectional. Kemudian sampel dalam penelitian ini sebanyak 30 pasien tuberkulosis paru yang terdiri dari pasien fase pengobatan 0 dan 6 bulan. Terdapat hubungan kadar C Reactive Protein dengan jumlah neutrofil pada penderita tuberkulosis paru dengan fase pengobatan 0 dan 6 bulan (p = 0,014, r= 0,370)
Pulmonary tuberculosis is still a health problem to control in the world. This disease is caused by the bacterium Mycobacterium tuberculosis, which can cause inflammation that can trigger increased levels of C-Reactive Protein and leukocytes in the body. This study was conducted to determine the correlation between C-Reactive Protein levels and the number of leukocytes with treatment phases 0 and 2 months in BKPM Purwokerto. The design of this study was an analytical observation with a cross-sectional research design. Results from 30 pulmonary tuberculosis patients treated for 0 and 2 months showed a correlation between CRP levels and white blood cell counts (p = 0.002, r = 0.445). There is a moderate relationship between CRP levels and leukocyte counts. High levels of CRP correlate with increasing the number of leukocytes. More research is needed on the relationship between CRP levels and leukocyte counts with different phases of treatment.
Hemolisis yaitu pecahnya sel darah merah dan keluarnya hemoglobin ke plasma. Hemolisis dapat terjadi secara in vitro dan in vivo. Sampel yang hemolisis dapat mempengaruhi hasil pemeriksaan laboratorium yang dapat menyebabkan kesalahan diagnosis, terapi dan prevensi. Tujuan penelitian ini adalah untuk melihat pengaruh hemolisis terhadap nilai trombosit dengan menggunakan metode penghitungan serta penilaian trombosit dari sampel darah yang tidak lisis dan dilisiskan secara in vitro. Penelitian ini dilakukan secara eksperimental pada bulan Juli 2020 di Laboratorium Patologi Klinik Fakultas Kedokteran Universitas Muhammadiyah Purwokerto. Teknik pengambilan sampel dilakukan secara purposive sampling sebanyak 14 sampel.Perhitungan nilai trombosit dilakukan menggunakan metode penghitungan langsung.
The prevalence of allergies is increasing from year to year due to the modern lifestyle in society. The incidence of allergies was influenced by several factors, such as genetics, age, sex, diet, food type, and also environmental factors. Determination of IgE levels in adolescents and young adults is important because the incidence of allergy is highly reported in adolescents and young adults. This study was conducted to determine IgE levels in allergies among university students in Universitas Muhammadiyah Purwokerto. This observational study was conducted among diploma students of Medical Laboratory Technology, Universitas Muhammadiyah Purwokerto. The data of characteristic subjects were collected by a self-administered questionnaire whereas data of IgE levels were collected by serum samples and measured by ELISA. A total of 23 students (4.35 % male and 95.65% female) were included. Seafood allergy (25%) were the commonest allergy among the students. Only 9% of subjects have combination allergies. The highest of IgE levels were 365 IU/mL.
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Pulmonary TB has become a health problem worldwide, including in Indonesia, because the sufferers' prevalence is increasing every year. The increase in TB drug resistance will pose a severe health threat. The continuous consumption of drugs in large quantities and high doses can affect the function of the thyroid gland. This study aimed to determine the levels of thyroid stimulating hormone (TSH) in pulmonary tuberculosis patients with treatment phases of 0 months and six months. This research is analytical observational research with a cross-sectional research design. The sampling method uses accidental sampling. A total of 42 respondents participated in this study to determine the levels of TSH in pulmonary TB. The results of the Mann-Whitney U test showed no difference in TSH levels in pulmonary TB patients with different treatment phases of 0 months and six months (p = 0.3). There was no significant difference between TSH levels in pulmonary TB patients in the 0 and 6-month treatment phases.
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