A peptide b 2 -m 21À31 , which is a fragment from residue 21 to residue 31 of b 2 -microgloblin, is experimentally known to self-assemble and form amyloid fibrils. In order to understand the mechanism of amyloid fibril formations, we applied the replica-exchange molecular dynamics method to the system consisting of three fragments of b 2 -m 21À31 . From the analyses on the temperature dependence, we found that there is a clear phase transition temperature in which the peptides aggregate with each other. Moreover, we found by the free energy analyses that there are two major stable states: One of them is like amyloid fibrils and the other is amorphous aggregates.
NTT is promoting research and development to enable people with various physical conditions, including disabilities, to enjoy watching sports. Focusing on goalball, which is a type of parasport, this article introduces a new experience of sports watching that provides a sense of realism as if the spectators were watching the game at the competition venue. This experience is possible by using ultra-realistic communication technology called Kirari! (particularly, highly realistic sound-image localization technology) for producing stereophonic sound.
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