SUMMARYThis paper studies the hypercrossbar network which has high flexibility and extensibility as a massively parallel computer network. Its performance is evaluated in nonroutine processing by computer simulation and theoretical analysis. To improve its performance, an implementation method of adaptive routing based on dynamic path determination is proposed, and its performance is evaluated by computer simulation. It is verified that the hypercrossbar network with adaptive routing has about 45 percent of the peak throughput at random transfer. Furthermore, its effectiveness is extremely high for applications with hotspot. It can attain about 8 times throughput compared with fixed routing.
Cardiovascular depression occurring when diazepam is combined with fentanyl has been investigated using the benzodiazepine antagonist RO15-1788 in the dog. After the initial administration of fentanyl (40 mcg/kg), the mean arterial pressure (MAP) decreased to 89% of its control value. Following the administration of diazepam (1.2 mg/kg), the MAP and the total peripheral resistance (TPR) decreased significantly, to 75% and 83% of their control values respectively. After the administration of RO15-1788 (0.4 mg/kg), the MAP increased significantly to 90% and the TPR to 102% of their control values and, lastly, the administration of naloxone (40 mcg/kg) increased the MAP to 108% of its control value. No relationship was found between the changes in the catecholamines and the changes in the MAP after the administration of fentanyl, diazepam, and RO15-1788. The mechanism of circulatory depression when diazepam was used with fentanyl is interpreted as being a peripheral vasodilatory effect of diazepam acting by way of the benzodiazepine receptors since RO15-1788 was found to antagonize this effect.
Atlanto-AxialRotatory Fixation (AARF) would occur with many causes including minor trauma to the neck and infection and so on. We experienced a case of AARF which developed in course of the treatment of Herpes Zoster. A 12 years old girl was transfered our Pain Clinic because she complained neck pain and torticollis associated with severe moving pain two weeks after the development of Herpes Zoster in the left C2 region. The etiologic factor of AARF in this patient could be refractory fixation and minor trauma associated with HZ-induced pain and infiltration caused by HZ virus. The patient responded very well to nerve block therapy including cervical epidural block and rehabilitation, AARF resolved with in a month. Since the early diagnosis and therapy of this disorder is important especially in young patient, we should be aware that patient with HZ of cervical region may develope AARF due to pain and refractory fixation and infiltration of HZ virus itself.
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