Lymphadenopathy after treatment of malignancy is not a definitive sign of recurrence. Therefore, pathological sampling and diagnosis are essential for determining the appropriate treatment. For this purpose, EUS-FNA is a safe, convenient, and minimally invasive procedure with high diagnostic value.
An extremely rare case of esophageal metastasis from prostate cancer is reported. A 65-year-old man presented with anorexia and back pain. Upper gastrointestinal X-ray fluoroscopy and endoscopy revealed a shallow longitudinal ulcer, with converging mucosal folds, approximately 5 cm above the esophagogastric junction. The histological diagnosis of the biopsied specimen was adenocarcinoma. Blood biochemistry revealed elevated serum prostate-specific antigen (PSA) and gamma-seminoprotein levels. Ultrasonography of the prostate disclosed a hypoechoic lesion in the left lobe, and needle biopsy led to the diagnosis of prostatic adenocarcinoma. Since there was no finding suggestive of a primary lesion, apart from that in the prostate, we conducted reverse transcriptase-polymerase chain reaction (RT-PCR) for PSA. PSA-positive mRNA was demonstrated in the tissue of the esophageal tumor. There are three reports on metastasis to the esophagus from prostate cancer, but this is the first case of esophageal metastasis from prostate cancer without any evidence of metastasis to other organs. The importance of RT-PCR for the diagnosis of primary lesions of metastatic cancer is discussed.
Abstract-Techniques for the optimal design of permanent magnet motors considering rotation are investigated. The nonconforming mesh technique is used to take into account the rotation of rotor. It is shown that the technique is especially useful for the optimal design using the finite element method, because no modification of mesh is necessary during the rotation. The mesh at each angle of rotation can be obtained by only combining meshes of a rotor and a stator. By using the combined optimization technique of the experimental design method and the Rosenbrock's method, the number of FEM calculations can be fairly reduced. By applying the optimal design method, about 40% of volume of permanent magnet of IPM motor and about 15% of the torque ripple can be reduced.
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