Purpose: Our study aimed to examine the impacts of blood cardioplegia (BC) and del Nido cardioplegia (DNC) solutions, which we used in isolated coronary artery bypass grafting, on early mortality and major adverse events. Material and method: We retrospectively analyzed 329 consecutive patients who underwent coronary artery bypass grafting (CABG) operations in our clinic between January 2016 and January 2020. Myocardial infarction, reoperation, cardiac tamponade, stroke, renal failure, extracorporeal membrane oxygenator requirement, and cardiopulmonary resuscitation were defined as major adverse events. The group for which del Nido cardioplegia was used was named Group D, and the group for which blood cardioplegia was used was named Group B. Group D consisted of 181 (55%) patients, and Group B consisted of 141 (45%) patients. Results: No statistically significant difference was determined between the groups regarding age, weight, body surface area, gender, or EuroSCORE ( p=.615, p=.560, p=.934, p=.365, p=.955, respectively). Although there was no statistically significant difference between the groups in terms of aortic cross-clamp time ( p=.712), the cardiopulmonary bypass duration was longer in Group B ( p=.001). Even though the incidence of stroke was higher in Group B ( p=.030), no statistically significant difference was observed between the groups regarding the total incidence of major adverse events, mortality, mechanical ventilation time, length of stay in the intensive care unit, or length of hospital stay ( p=.153, p=.130, p=.689, p=.710, p=.613, respectively). Conclusion: We found no significant difference in MAE, mortality, duration of MV, ICU stay, or hospitalization in the DNC and BC groups. We believe that both solutions can be used safely for cardiac protection in the adult patient population.
Purpose The primary aim of this study was to examine the effects of two oxygenator systems on major adverse events and mortality. Methods A total of 181 consecutive patients undergoing coronary artery bypass grafting in our clinic were retrospectively analyzed. The patients were divided into two groups according to the oxygenator used: Group M, in which a Medtronic Affinity (Medtronic Operational Headquarters, Minneapolis, MN, USA) oxygenator was used, and Group S, in which a Sorin Inspire (Sorin Group Italia, Mirandola, Italy) oxygenator was used. Results Group S consisted of 89 patients, whereas Group M included 92 patients. No statistically significant differences were found between the two groups in terms of age ( p = .112), weight ( p = .465), body surface area ( p = .956), or gender ( p = .484). There was no statistically significant difference in hemorrhage on the first or second postoperative day ( p = .318 and p = .455, respectively). No statistically significant differences were observed in terms of red blood cell ( p = .468), fresh frozen plasma ( p = .116), or platelet concentrate transfusion ( p = .212). Infections, wound complications, and delayed sternal closure were significantly more common in Group M ( p = .006, p = .023, and p = .019, respectively). Extracorporeal membrane oxygenators and intra-aortic balloon pumps were required significantly more frequently in Group S ( p = .025 and p = .013, respectively). Major adverse events occurred in 16 (18%) patients in Group S and 14 (15.2%) patients in Group M ( p = .382). Mortality was observed in six (6.7%) patients in Group S and three (3.3%) patients in Group M ( p = .232). No statistically significant difference was found between the two groups in terms of length of hospital stay ( p = .451). Conclusion The clinical outcomes of the two oxygenator systems, including mortality, major adverse events, hemorrhage, erythrocyte and platelet transfusions, and length of hospital stay, were similar.
BackgroundCarotid artery stenosis is one of the most important causes of stroke, and atherosclerosis plays a role in one third of all strokes. It has been reported in some studies that the patency rate of carotid endarterectomies performed with patplasty is better than standard surgical treatment. In this retrospective study, we investigated vascular patency rates and strokes due to postoperative restenosis in patients who underwent classical carotid endarterctomy and patch plasty endarterctomy due to carotid artery stenosis.We investigated 126 patients diagnosed with carotid artery occlusion between January 2015 and January 2021. We retrospectively analyzed and compared 44 patients who were operated on using carotid endarterectomy (CAE) with patch technique and 82 patients who underwent only carotid endarterectomy in terms of risk factors, restenosis and stroke. Color Doppler Ultrasonography (CDUS) and Computed Tomographic Angiography (CTA) were used in the diagnosis of carotid artery occlusions and the evaluation of restenosis.Results:The characteristics of the risk factors of the patients were examined and recorded. PTFE graft was used as a patch in patients. There were no significant complications during or after the operation. Restenosis and stroke were investigated at the 10th day, third month, sixth month, and first year after discharge, and mostly by imaging with CDUS. Restenosis was detected in one patient in the study group and in thirteen patients in the control group. Stroke was detected in none of the patients in the study group and in four patients in the control group.Conclusion: In our clinic, patch-based CAE is preferred to primary CAE due to its successful results and very low risk of restenosis. We think that CAE with the patch is a much more effective method in protecting patients from neurological pathologies.
ÖZAmaç: Bu çalışmada, akut mezenterik iskemi nedeniyle ameliyat edilen hastalarda superior mezenterik arter tromboembolisinin ameliyat sonuçları ve mortaliteyi etkileyen faktörler değerlendirildi.Ça lış ma pla nı: Ocak 2011 -Aralık 2016 tarihleri arasında akut mezenterik iskemi tanısı konan ve ameliyat edilen ardışık 28 hasta (15 erkek, 13 kadın; ort. yaş 71.2±10 yıl; dağılım 48-89 yıl) çalışmaya alındı. Açık revaskülarizasyon işlemlerinin sonuçları ve mortaliteyi etkileyen faktörler retrospektif olarak değerlendirildi. Bul gu lar:En sık şikayet karın ağrısını takiben bulantı ve kusma idi. Tanı, bilgisayarlı tomografi anjiyografi ve Dupleks ultrasonografi ile doğrulandı. Hastaların çoğunluğunda tromboembolektomi yapılırken, uygun hastalarda otolog safen ven baypas ve transpozisyon uygulandı. Revaskülarizasyon işlemleri 10 hastada bağırsak rezeksiyonunu engelledi. Solunum, böbrek ve kalp patolojilerine bağlı mortalite oranı %35.7 idi. Ameliyat sonrası solunum yetmezliği ve karın ağrısı başlangıcından sonra altı saatten daha geç hastaneye başvuru, mortaliteyi etkileyen faktörler olarak bulundu.So nuç: Çalışma sonuçlarımız ameliyat sonrası solunum yetmezliği ve karın ağrısı başlangıcından sonra geç başvurunun ameliyat sonrası mortalite ile ilişkili olduğunu gösterirken, bağırsak rezeksiyon gereksiniminin mortalite oranlarına bir etkisi gözlenmedi. Çalışma sonuçlarımıza göre, keşif amaçlı laparotomi ve tromboembolektominin, bağırsak canlılığını değerlendirmede ve mezenterik perfüzyonun devamında önemli olduğu kanısındayız.Anah tar söz cük ler: Embolektomi; mezenterik iskemi; superior mezenterik arter. ABSTRACT Background:In this study, we aimed to evaluate the operative results of superior mesenteric artery thromboembolism and influential factors for mortality in patients undergoing surgery for acute mesenteric ischemia.
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