The endoscopic atrophic border is a boundary between the pyloric and fundic gland territories, which is endoscopically recognized by discriminating differences in color and height of the gastric mucosa. The existence of superficial gastritis might exag-gerate the color and niveau differences, thus making it much easier to recognize the atrophic border. And also, according to the results of precise biopsy taken perpendicularly across the endoscopic atrophic border, it might be the boundary of histological atrophy and nonatrophy. In other words, the endoscopic atrophic border might be the boundary both of gland type and of atrophy. As a supplemental approach, a selective application of congo red method was endoscopically performed, which suggests that this might be a physiological border as well.Additionally, a classification of the atrophic pattern was attempted according to the location of the endoscopic atrophic border in the stomach, which revealed a close relationship with gastric analysis.Endoscopy 3 (1969) 87-97

A satisfactorily high H. pylori eradication rate was obtained in Japanese ulcer patients with the triple therapy regimen consisting of LPZ 30 mg, AMPC 750 mg, and CAM 200 mg b.i.d.

Light and electron microscopic changes in human liver cells which were considered to be precancerous lesions, were studied. In our micrometrical examination, dysplastic liver cells were classified into two types: large and small dysplastic cell. Each type had nuclear pleomorphism and multinucleation; however, the nucleocytoplasmic ratio of the large dysplastic cell remained normal. Electron microscopically, the large dysplastic cell had some features of regenerative cells. The nucleocytoplasmic ratio of the small dysplastic cell was between that of normal hepatocytes and liver cancer cells. The difference in the incidence of the small and large dysplastic cells in normal livers and cirrhotic livers having hepatocellular carcinoma was statistically significant. In addition, the small dysplastic cell had more of a tendency to produce a small round focus. It was morphologically suggested that the more important candidate for the precancerous cell in the liver was the small dysplastic cell.

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