Abstmct-Cultured JTC-3 cells of human amniotic cell origin were irradiated with CW ultrasound intensities of 1 W/cm2 (SATA) or more. Cell growth was suppressed when the cells, suspended in phosphate buffered saline, were sonicated while being rotated at 2.5 rpm in a polystyrene tube for 60 min. Dead cells were rarely found after staining and cell colony formation showed no significant decrease. The slow rotation of the cells and the intrinsic nature of the cells may he the reason for this phenomenon. Using the same experimental model, pulsed ultrasound suppressed cell growth at intensities of 240 rnW/cmz (SPTA), 20 Wlcm' (SATP), and 80 W/cm2 (SPTP) using a pulse duration of 3 ps and a pulse repetition frequency of LOO0 Hz.
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